Results 51 to 60 of about 345,766 (300)

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

Advanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian, Vicky L. Schiling, Thomas Muley, Michael Allgäuer, Florian Eichhorn, Michael Meister, Marc A. Schneider, Anna A. Popova   +7 more
wiley   +1 more source

Quantitative evaluation method of structural safety status of ancient Chinese three-hole stone arch bridges—A case study of the Yongchang Bridge

Journal of Asian Architecture and Building Engineering, 2023
A study is presented on a quantitative evaluation method of structural safety for an existing three-hole stone arch bridge, in order to determine the structural safety status of this type of stone arch bridges and provide a scientific basis for their ...
Chun Qing, Jin Hui, Wu Yuande, Han Yidan, Mi Zhendong, Chen Qi, Ma Shiyu   +6 more
doaj   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Environmental factors in image-based soil analysis: Interaction effects of moisture, texture, and illumination

Geoderma
Image-based characterization of Soil Organic Matter (SOM) has been significantly influenced by varying ambient environmental conditions, moisture levels and texture, with the interplay between these factors remaining largely understudied.
Mojtaba Naeimi, Prasad Daggupati, Maja Krzic, Stacey Scott, Hiteshkumar Vasava, Daniel Saurette, Asim Biswas   +6 more
doaj   +1 more source

Phosphate-based treatments for conservation of stone

RILEM Technical Letters, 2017
To overcome the limitations of currently available protectives and consolidants for carbonate stones (such as marble and limestone), in 2011 the use of calcium phosphate was proposed. The idea is forming calcium phosphates (ideally hydroxyapatite) as the
Enrico Sassoni
doaj   +1 more source

The building stones and slates of Killin : an investigation of stone for the built heritage [PDF]

, 2010
The village of Killin lies in an area of dramatic landscape and mountain scenery. The use of local stone in the buildings gives a direct connection to this landscape and reflects the local geology, comprising mostly metamorphic rocks of Precambrian age
Albornoz-Parra, L.J., Custance-Baker, A.B., Everett, P., Hyslop, E.K., Parry, S.F., Tracey, E.A.   +5 more
core  

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Environmental microscopy in stone conservation

Scanning, 1996
AbstractThe natural weathering of stone is accelerated by the combined effects of acid rain, salt crystallization, and the freeze‐thaw cycles of water. Since weathering will take place until the system reaches chemical equilibrium, we can mitigate the loss to historic stone monuments and structures by treatments of the stone that retard hydrolysis and ...
Sudeep M. Rao, C. Jeffrey Brinker, Timothy. J. Ross   +2 more
openaire   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source