Results 61 to 70 of about 345,766 (300)

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

〔報告〕凝灰岩製石造文化財における劣化現象認識のための注意点—京都市個人所蔵石殿の一事例を通して— [PDF]

, 2013
An investigation was carried out on a stone shrine made of tuff where weathering and erosion are advancing severely. Three-dimensional measurement and survey of old photographs suggest that the shrine has eroded rapidly during these 5 years.
朽津 信明, 森井 順之, 津村 宏臣   +2 more
core   +1 more source

A practical method for preparing Ca(OH)2 nanodispersions for the consolidation of archaeological calcareous stones [PDF]

, 2018
Exposure to atmospheric conditions results in considerable deterioration of calcareous building stones, lime mortars and plasters in archaeological monuments, requiring several conservation treatments.
Caner, Evin, Caner-Saltık, E.N.
core   +1 more source

Introduction to the Stone Cycle and the Conservation of Historic Buildings [PDF]

Quarterly Journal of Engineering Geology and Hydrogeology, 2013
This Thematic Set of papers relating to the life cycle of building stone was initiated by a call for papers in order to better recognize the contribution that the disciplines, and practitioners, of engineering geology and hydrogeology make to the conservation of historical buildings, which is intrinsically multidisciplinary.
Cassar, J., Winter, M. G., Marker, B. R., Bromhead, E. N., Smith, J. W. N., Toll, D. G., Walton, Nick, Entwisle, D. C., Dijkstra, T. A.   +8 more
openaire   +3 more sources

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues

Advanced Science, EarlyView.
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak, Ashley D. Westerfield, Vardhman Kumar, Kasturi Chakraborty, Navaneeth Krishna Rajeeva Pandian, Christopher S. Chen, Sangeeta N. Bhatia   +6 more
wiley   +1 more source

A Novel Approach to Carbonate Stone Conservation: Induced Calcium Oxalate Formation Through the Application of Ammonium N-Ethyloxamate (AmEtOxam) on White Carrara Marble

Molecules
Ammonium N-ethyloxamate (AmEtOxam) was synthesized, fully characterized by microanalytical and spectroscopic means, and assayed as a precursor of calcium oxalate, acting as a protecting agent for white Carrara marble.
Simone Murgia, M. Carla Aragoni, Gianfranco Carcangiu, Laura Giacopetti, Domingo Gimeno Torrente, Vito Lippolis, Eleonora Loi, Paola Meloni, Antonia Navarro Ezquerra, Enrico Podda, Anna Pintus, Riccardo Serra, Massimiliano Arca   +12 more
doaj   +1 more source

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

Advanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao, Dalin Chen, Ziyi Zhang, Jingxuan Ren, Chengcheng Zhao, Shengfang Wang, Mengyu Shang, Dawei Jiang, Yinuo Li, Su'an Tang, Kai Li, Xiaohui Zhang, Xiaogang Wang   +12 more
wiley   +1 more source

〔報文〕過去の高松塚古墳石室内の温湿度変動解析（3）―吸放熱パネルへの送水温度および入室が石室内温湿度変動に与える影響― [PDF]

, 2010
In order to investigate the causes of deterioration of the mural paintings of Takamatsuzuka Tumulus, it is very important to clarify temperature and humidity variation in the stone chamber.
小椋 大輔, 李 永輝, 石崎 武志, 鉾井 修一   +3 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source