Results 81 to 90 of about 270,897 (278)
, 2016 Translational readthrough gives rise to C-terminally extended proteins, thereby providing the cell with new protein isoforms. These may have different properties from the parental proteins if the extensions contain functional domains.
Gärtner, J. +6 more
core +2 more sources
Different stop codon usage in two pseudohypotrich ciliates [PDF]
FEMS Microbiology Letters, 2001 Based on rRNA phylogeny, morphologic and morphogenetic characters, two major groups of hypotrich ciliates can be distinguished: euhypotrichs and pseudohypotrichs. Through the sequencing of actin genes, we show here that, interestingly, the pseudohypotrichs Dyophrys sp. and Euplotes vannus have a different stop codon usage. In fact, the stop codon usage
P, Perez-Romero, E, Villalobo, A, Torres
openaire +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Chirality in a quaternionic representation of the genetic code [PDF]
, 2015 A quaternionic representation of the genetic code, previously reported by the authors, is updated in order to incorporate chirality of nucleotide bases and amino acids.
Carlevaro, C. Manuel +2 more
core +2 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
On the origin of the mitochondrial genetic code: Towards a unified mathematical framework for the management of genetic information [PDF]
, 2012 The origin of the genetic code represents one of the most challenging problems in molecular evolution. The genetic code is an important universal feature of extant organisms and indicates a common ancestry of different forms of life on earth.
Diego Luis Gonzalez +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
REPARATION : ribosome profiling assisted (re-)annotation of bacterial genomes [PDF]
, 2017 Prokaryotic genome annotation is highly dependent on automated methods, as manual curation cannot keep up with the exponential growth of sequenced genomes.
Giess, Adam +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
The complete mitochondrial genome of Pontia edusa (Lepidoptera: Pieridae)
Mitochondrial DNA. Part B. Resources, 2021 The complete mitochondrial genome of Pontia edusa was sequenced and analyzed in the study. The length of the complete mitogenome is 15,125 bp, including 37 genes and a control region.
Ju-Ping Wang +3 more
doaj +1 more source