Results 91 to 100 of about 293,690 (314)

Stopping antidepressants safely

African Journal of Primary Health Care & Family Medicine
Long-term antidepressant pharmacotherapy is frequently continued beyond guideline-recommended durations. This occurs particularly among women, despite limited evidence of ongoing benefit for many people treated for mild-to-moderate depression and an ...
Mark Horowitz, Thomas L. Perry
doaj   +1 more source

Non-inertial stopping characteristics of a prototype pump

Advances in Mechanical Engineering, 2019
The characteristics of centrifugal pump in non-inertial stopping period have not been studied better by far. In this article, the variation characteristics of transient performance of a prototype pump are clarified experimentally in five non-inertial ...
Yu-Liang Zhang, Zu-Chao Zhu, Wen-Guang Li, Xiao-Qi Jia   +3 more
doaj   +1 more source

Nuclear reaction analyses for green chemistry: Evaluating environmental safety in charged particle interactions [PDF]

E3S Web of Conferences
The total stopping power, range and stopping time were calculated using relativity theory equation of Betha's at energies ranging from 1 MeV to 1000 MeV.
Hussain Fatima, Meteab Mohanad
doaj   +1 more source

Random Stopping Times in Stopping Problems and Stopping Games

, 2012
Three notions of random stopping times exist in the literature. We introduce two concepts of equivalence of random stopping times, motivated by optimal stopping problems and stopping games respectively. We prove that these two concepts coincide and that the three notions of random stopping times are equivalent.
Solan, Eilon, Tsirelson, Boris, Vieille, Nicolas   +2 more
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

An optimal stopping problem in a diffusion-type model with delay [PDF]

We present an explicit solution to an optimal stopping problem in a model described by a stochastic delay differential equation with an exponential delay measure. The method of proof is based on reducing the initial problem to a free-boundary problem and
Pavel V. Gapeev, Markus Reiß
core  

Stopping domains [PDF]

, 1997
Se estudian algunos conceptos básicos y resultados no-estándar sobre dominios, líneas y puntos de parada en análisis estocástico con dos parámetros.When we are working in a two parameter stochastic analysis, we do not have only stopping points.
Muñoz, Myriam
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source