Results 71 to 80 of about 339,219 (259)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Recursive Optimal Stopping with Poisson Stopping Constraints [PDF]
This paper solves a recursive optimal stopping problem with Poisson stopping constraints using the penalized backward stochastic differential equation (BSDE) with jumps.
Wei, Wei +3 more
core +4 more sources
An Empirical Study on the Correlation between Early Stopping Patience and Epochs in Deep Learning [PDF]
ITM Web of ConferencesEarly stopping is a technique used to prevent overfitting in deep learning models by stopping the training process when the validation loss stops improving.
Hussein Bootan M., Shareef Shareef M.
doaj +1 more source
Optimal stopping in Levy models, for non-monotone discontinuous payoffs [PDF]
We give short proofs of general theorems about optimal entry and exit problems in Levy models, when payoff streams may have discontinuities and be non-monotone.
Boyarchenko, Svetlana +1 more
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
IEEE Photonics Journal, 2019 Optical stopping can serve as a light-controlled solution to implementing photonic components. In contrast to saturated optical stopping that provides enough excited electrons to entirely absorb signal lights, unsaturated optical stopping introduces a ...
Zhi Chen, Guande Wang, Xiong Wang
doaj +1 more source
The influence of dopaminergic polymorphisms on selective stopping
, 2019 Although the genetic influence on global stopping has been extensively investigated, little is known about the genetic contribution to other more complex forms of inhibitory control such as selective stopping. The selectivity of inhibitory control can be
Sánchez Carmona, Alejandro +6 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Stopping antidepressants safely
African Journal of Primary Health Care & Family MedicineLong-term antidepressant pharmacotherapy is frequently continued beyond guideline-recommended durations. This occurs particularly among women, despite limited evidence of ongoing benefit for many people treated for mild-to-moderate depression and an ...
Mark Horowitz, Thomas L. Perry
doaj +1 more source
Non-inertial stopping characteristics of a prototype pump
Advances in Mechanical Engineering, 2019 The characteristics of centrifugal pump in non-inertial stopping period have not been studied better by far. In this article, the variation characteristics of transient performance of a prototype pump are clarified experimentally in five non-inertial ...
Yu-Liang Zhang +3 more
doaj +1 more source