Results 181 to 190 of about 106,679 (252)

A Bayesian Adaptive Design for Assessing Treatment Effect Consistency in Bridging Studies. [PDF]

Stat Med
He X, Zhao D, Teng Z, Liu H, Yuan Y.
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Reproducible study identification and selection in systematic reviews: barriers and paths forward. [PDF]

BMJ Open
Lin L, Xing X, Wu C, Chen Y, Tong J, McClelland DJ, Chen Z.   +6 more
europepmc   +1 more source

Deep‐Learning‐Based Denoising for Improved Phase Precision in Electron Holography of Electromagnetic Fields in Nanoscale Materials

Advanced Science, EarlyView.
Low‐dose electron holography is limited by shot noise, which buries weak phase signals. HoloDenoiser, a physics‐informed network that works simultaneously in the spatial and frequency domains, locates and protects the holographic sideband while suppressing noise in the hologram.
Ye Luo, Luyang Wang, Zhiling Yu, Xiaowen Chen, Xiaoyu Wang, Ya‐Hui Jia, Thibaud Denneulin, Yu Han, Rafal E. Dunin‐Borkowski, Fengshan Zheng, Qi Liu   +10 more
wiley   +1 more source

Gradient boosting-based discrete failure time model for selecting time-varying effects and interactions. [PDF]

Lifetime Data Anal
Luo L, He K, Taylor JMG.
europepmc   +1 more source

Decoupling Fabrication From Encoding: DNA‐Addressable Template Microparticles for Large, User‐Defined Optical Barcode Libraries

Advanced Science, EarlyView.
A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi, Yuichiro Iwamoto, Hinata Tokuda, Haruka Narita, Adrian M. Martin, Sadao Ota   +5 more
wiley   +1 more source

Implementation of procalcitonin-guided antibiotic stopping advice in sepsis: A mixed-methods process evaluation in a clinical trial context. [PDF]

J Intensive Care Soc
Poole RL, Lloydwin C, Anderson H, Dark P, Lall R, Hossain A, White J.   +6 more
europepmc   +1 more source

Quantum‐Trained AI Enables Inverse Design of Organic Frontier Orbitals at Billion‐Scale

Advanced Science, EarlyView.
Quantum‐trained AI links molecular substructures to frontier‐orbital energetics and enables interpretable screening across nearly one billion GDB‐13 molecules. By combining fragment‐ and ring‐level insights with donor–acceptor energy alignment against ITIC, the framework narrows an immense chemical space to a small set of promising candidates and ...
Yeongnam Ko, Se Jin Kim, Ki Chul Kim
wiley   +1 more source

To include or not to include? A prescription from the pharmacy on how to use active learning-assisted screening in systematic reviews. [PDF]

Syst Rev
Verdonschot RG, Dilles T, Cahir C, De Graef M, Holis RV, Fryden J, Denig P, Grimes T, Karapinar-Carkıt F, Schor M.   +9 more
europepmc   +1 more source