Results 51 to 60 of about 37,831 (263)

Improvement and evaluation of polymer-matrix composite panels with hat stiffeners

MATEC Web of Conferences, 2016
Hat-stiffened composite panels fabricated by co-curing technologies are widely used in the fuselage panel due to the good structural stability and high efficiency of axial load transferring.
Li S. J., Zhan L. H., Ding X. X., Chen F., Peng W. F., Zhang Y. A., Pu Y. W., Liu X. Y.   +7 more
doaj   +1 more source

Alternative stopping rules to limit tree expansion for random forest models

Scientific Reports, 2022
Random forests are a popular type of machine learning model, which are relatively robust to overfitting, unlike some other machine learning models, and adequately capture non-linear relationships between an outcome of interest and multiple independent ...
Mark P. Little, Philip S. Rosenberg, Aryana Arsham   +2 more
doaj   +1 more source

Expectation and Optimal Allocations in Existential Contests of Finite, Heavy-Tail-Distributed Outcomes

Mathematics, 2023
Financial time series and other human-driven, non-natural processes are known to exhibit fat-tailed outcome distributions. That is, such processes demonstrate a greater tendency for extreme outcomes than the normal distribution or other natural ...
Ralph Vince
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Adaptivní nepřesné newtonovy metody s a posteriorními zastavovacími kritérii [PDF]

ACC Journal, 2012
V této práci uvažujeme systémy nelineárních algebraických rovnic vznikající při numerické diskretizaci nelineárních parciálnich diferenciálních rovnic difúzního typu.
Alexandre Ern, Vohralík. Martin
doaj  

Artificial intelligence in systematic reviews: promising when appropriately used

BMJ Open, 2023
Background Systematic reviews provide a structured overview of the available evidence in medical-scientific research. However, due to the increasing medical-scientific research output, it is a time-consuming task to conduct systematic reviews.
Job van der Palen, Carine J M Doggen, Sanne H B van Dijk, Marjolein G J Brusse-Keizer, Charlotte C Bucsán, Anke Lenferink   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

An intrinsic stopping criterion for committee-based active learning [PDF]

Proceedings of the Thirteenth Conference on Computational Natural Language Learning - CoNLL '09, 2009
As supervised machine learning methods are increasingly used in language technology, the need for high-quality annotated language data becomes imminent. Active learning (AL) is a means to alleviate the burden of annotation. This paper addresses the problem of knowing when to stop the AL process without having the human annotator make an explicit ...
Olsson, Fredrik, Tomanek, Katrin
openaire   +4 more sources

Exploiting Trade-Off Criteria to Improve the Efficiency of Genetic Multi-Objective Optimisation Algorithms

Frontiers in Chemical Engineering, 2021
The highly competitive nature of the chemical industry requires the optimisation of the design and exploitation of (bio-)chemical processes with respect to multiple, often conflicting objectives. Genetic algorithms are widely used in the context of multi-
Viviane De Buck, Philippe Nimmegeers, Ihab Hashem, Carlos André Muñoz López, Jan Van Impe   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source