Results 41 to 50 of about 53,594 (285)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Jets in a strongly coupled anisotropic plasma

open access: yesEuropean Physical Journal C: Particles and Fields, 2018
In this paper, we study the dynamics of the light quark jet moving through the static, strongly coupled $${\mathcal {N}}=4$$ N=4 , anisotropic plasma with and without charge.
Kazem Bitaghsir Fadafan, Razieh Morad
doaj   +1 more source

Three-Dimensional Stopping Sight Distance Calculation Method under High Slope Restraint

open access: yesApplied Sciences, 2020
Sight distance is an important indicator to ensure the safety of drivers, and is also an indispensable evaluation basis in highway safety engineering.
Yonghong Yang   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Simulation-based estimation of an automotive magnetorheological brake system performance

open access: yesJournal of Advanced Research, 2018
Magnetorheological (MR) brakes, owing to their quick response, are being investigated as a possible candidate for substitution for the conventional hydraulic brakes of road vehicles. The MR brake system for a two-wheeler application was envisaged in this
Shital M. Kalikate   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A REVIEW OF THE ANTI-LOCK BRAKE DIAGNOSIS SYSTEM AND ITS CONTROL TECHNIQUES [PDF]

open access: yesJournal of the Egyptian Society of Tribology
The brake system is one of the important systems in vehicles because of its importance in stopping the car in the shortest stopping distance. Some appropriate systems help the brake system work to reduce the stopping distance.
Hamdy Abo El daheb   +2 more
doaj   +1 more source

Unsupervised GAN epoch selection for biomedical data synthesis

open access: yesCurrent Directions in Biomedical Engineering, 2023
Supervised Neural Networks are used for segmentation in many biological and biomedical applications. To omit the time-consuming and tiring process of manual labeling, unsupervised Generative Adversarial Networks (GANs) can be used to synthesize labeled ...
Böhland Moritz   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The influence of depressed mood on stopping distance in stop-sign and wall condition.

open access: yes, 2015
a. Group comparison. P-values are Bonferroni corrected for multiple comparisons. Black line is the target (stop-sign or wall). Blue bars represent the stopping distance of the 3 groups in stop-sign condition and red bars represent that in wall condition,
He Huang (50693)   +3 more
core   +1 more source

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