Results 71 to 80 of about 384,701 (284)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Bayesian Evaluation of Group Sequential Clinical Trial Designs [PDF]
, 2005 Clincal trial designs often incorporate a sequential stopping rule to serve as a guide in the early termination of a study. When choosing a particular stopping rule, it is most common to examine frequentist operating characteristics such as type I error,
Emerson, Scott S. +2 more
core +1 more source
Infinitesimal Look-Ahead Stopping Rules
The Annals of Mathematical Statistics, 1971 Abstract : The continuous time optimal stopping problem is considered and an infinitesimal look ahead procedure is defined. Sufficient conditions are then given which ensure that this procedure, which is the continuous time analogue of the one stage look ahead rule in the discrete time problem, is optimal.
openaire +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Secretary Problem with Possible Errors in Observation
Mathematics, 2020 The classical secretary problem models a situation in which the decision maker can select or reject in the sequential observation objects numbered by the relative ranks.
Marek Skarupski
doaj +1 more source
Unit roots and multiple structural breaks in real output [PDF]
Utilizing re-sampling. Methods, we present evidence on the rejection probabilities for difference-stationary and trend-stationary models for Mexico’s real and real per-capita annual gross domestic product.
Antonio E. Noriega +1 more
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimal Selling Rule in a Regime Switching Lévy Market
International Journal of Mathematics and Mathematical Sciences, 2011 This paper is concerned with a finite-horizon optimal selling rule problem when the underlying stock price movements are modeled by a Markov switching Lévy process.
Moustapha Pemy
doaj +1 more source
BMC Medical Research Methodology, 2016 Background Multi-Arm Multi-Stage designs aim at comparing several new treatments to a common reference, in order to select or drop any treatment arm to move forward when such evidence already exists based on interim analyses.
Louis Jacob +4 more
doaj +1 more source
Computing Bayesian predictive distributions: The K-square and K-prime distributions [PDF]
, 2006 The computation of two Bayesian predictive distributions which are discrete mixtures of incomplete beta functions is considered. The number of iterations can easily become large for these distributions and thus, the accuracy of the result can be ...
Lecoutre, Bruno, Poitevineau, Jacques
core +1 more source