Results 101 to 110 of about 6,857,881 (395)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
CAPM Beta, Size, Book-to-Market, and Momentum in Realized Stock Returns [PDF]
Measuring risk in the stock market context is one of the key challenges of modern finance. Despite the substantial significance of the topic to investors and market regulators, there is a controversy over what risk factors should be used to price assets ...
Dalibor Petr, Jiri Novak
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Lithium-ion battery fault diagnosis method based on KPCA-MTCN
工程科学学报The paper proposes a method based on kernel principal component analysis (KPCA) and multi-scale temporal convolution network (MTCN) for identifying faults in lithium-ion batteries, which is crucial for ensuring the safe and stable operation of energy ...
Qipeng TAN +5 more
doaj +1 more source
Information Efficiency of the Capital Market: a Stochastic Calculus Approach Evidence from the Czech Republic (in English) [PDF]
This paper deals with an important characteristic of the capital market: information efficiency. With the use of geometric Brownian motion, the authors run several projections of stock prices based on varying amount of historic information and compare ...
Vít Pošta, Zbynìk Hackl
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Unifying the ORR and OER with surface oxygen and extracting their intrinsic activities on platinum
Nature CommunicationsCommon half-cell measurements deliver oxygen reduction activities linked to the chosen scan rate, limiting their value for fundamental and comparative studies on platinum.
Benedikt Axel Brandes +4 more
doaj +1 more source
Cobb-Douglas Production Function: The Case of a Converging Economy [PDF]
The Cobb-Douglas production function is often used to analyse the supply-side performance and measurement of a country’s productive potential. This functional form, however, includes the assumption of a constant share of labor in output, which may be too
Dana Hájková, Jaromír Hurník
core