Results 91 to 100 of about 2,738,785 (308)

Collapse of large vapor bubbles [PDF]

open access: yes, 1982
The refilling of propellant tanks while in a low-gravity environment requires that entrapped vapor bubbles be collapsed by increasing the system pressure.
Dominick, S., Tegart, J.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Stability of PMR-polyimide monomer solutions [PDF]

open access: yes
The stability of alcohol solutions of norborneyl capped PMR-polyimide resins was monitored during storage at ambient and subambient temperatures. Chemical changes during storage were determined spectroscopically using nuclear magnetic resonance.
Alston, W. B.   +2 more
core   +1 more source

Seed quality and storage performance in mungbean and peanut : a thesis presented in partial fulfilment of the requirement for the degree of Master of Agricultural Science in Seed Technology, at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 1996
Five seedlots of mungbean and three seedlots of peanut were assessed for seed quality using six standard laboratory tests ie. purity analysis, seed moisture content, germination, seed health, and two vigour tests (accelerated ageing, and conductivity ...
Supradith, Uraiwan
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Viability of endophytic fungus in different perennial ryegrass (Lolium perenne) varieties kept in different storage conditions : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2017
Epichloë endophytes form symbiotic relationships with cool-season grasses of the Pooideae family and are known to synthesise a range of bio-protective alkaloids.
Kitson, Elizabeth Rose
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Total alcoholic acidity and pH tests as quality parameters in stored soybean grains

open access: yesPesquisa Agropecuária Tropical, 2016
Despite the technology available to agriculture, qualitative and quantitative losses occurring during post-harvest are still not controlled, and stored grains may undergo changes in their composition, due to storage conditions.
Maicon Marinho Vieira Araujo   +2 more
doaj   +1 more source

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