Results 221 to 230 of about 638,467 (318)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Effects of Different Calcium Preparations on Fresh-Cut Quality and Storage Quality of Starkrimson Apple. [PDF]

Plants (Basel)
Sun M, Wang F, Ci J, Liu Y, Li K, Wang D, Yu W, Zhuang Y, Xiao Y.   +8 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Prediction of Storage Quality and Multi-Objective Optimization of Storage Conditions for Fresh <i>Lycium barbarum</i> L. Based on Optimized Latin Hypercube Sampling. [PDF]

Foods
Mou X, Huang X, Ma G, Luo Q, Yang X, Xin S, Wan F.   +6 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Synergistic Effects of Microalgae and Probiotic Additives in Edible Coatings on Strawberry Storage Quality: Experimental and Molecular Docking Studies. [PDF]

Probiotics Antimicrob Proteins
Bağdat EŞ, Kahraman Ilıkkan Ö.
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Exposure to sub-zero temperatures down to -11 °C does not impact packed red cells storage quality. [PDF]

Sci Rep
Derkenne C, Vavasseur M, Javaudin O, Daniel Y, Corcostegui SP, Lely P, Ormes E, Desudde H, Pons S, Giannuzzo A, Heidet M, Vest P, Jost D, Dussiot M, de l'Espinay AM, Martinaud C, Amireault P.   +16 more
europepmc   +1 more source