Results 81 to 90 of about 5,420,398 (301)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Performance of a superamphiphobic self-cleaning passive subambient daytime radiative cooling coating on grain and oil storage structures. [PDF]

Heliyon, 2023
Cai Y, Zhang Z, Yang Z, Fang Z, Chen S, Zhang X, Li W, Zhang Y, Zhang H, Sun Z, Zhang Y, Li Y, Liu L, Zhang W, Xue X.   +14 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Indigenous storage structures

, 2009
225-229Indigenous practices play a vital role in sustainable agriculture development and are unique to a given culture of society. An exhaustive survey was conducted in dry tracts of Tamil Nadu to document the indigenous storage structures used by ...
Karpagam, D, Karthikeyen, C, Firdouse, S Ayisha, Veeraragavathatham, D   +3 more
core  

Inclusion of CoTiO3 to ameliorate the re/dehydrogenation properties of the Mg–Na–Al system

Journal of Magnesium and Alloys
For the first time, the MgH2–NaAlH4 (ratio 4:1) destabilized system with CoTiO3 addition has been explored. The CoTiO3-doped MgH2–NaAlH4 sample begins to dehydrogenate at 130 °C, which is declined by 40 °C compared to the undoped MgH2–NaAlH4.
N.A. Ali, N.Y. Yusnizam, N.A. Sazelee, Sami-ullah Rather, Haizhen Liu, M. Ismail   +5 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Improving the charging performance of latent heat thermal energy storage systems using triply periodic minimal surface (TPMS) structures

The utilization of latent heat thermal energy storage (LHTES) using phase change materials (PCM) has attracted considerable attention due to their high energy density and thermal regulation.
Gado Mohamed Gaber Abdelsaid
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Suffix Tree Construction and Storage with Limited Main Memory [PDF]

, 2003
Schürmann K-B, Stoye J. Suffix Tree Construction and Storage with Limited Main Memory. Forschungsberichte. Bielefeld: Technische Fakultät der Universität Bielefeld; 2003.Suffix trees have been established as one of the most versatile index structures for
Schürmann, Klaus-Bernd, Stoye, Jens ; https://orcid.org/   +1 more
core