Results 61 to 70 of about 82,277 (194)

A novel characteristic of a phytoplankton as a potential source of straight-chain alkanes. [PDF]

Sci Rep, 2021
Harada N, Hirose Y, Chihong S, Kurita H, Sato M, Onodera J, Murata K, Itoh F.   +7 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Improved Solubility of Vortioxetine Using C2-C4 Straight-Chain Dicarboxylic Acid Salt Hydrates

Crystals, 2018
The purpose of this study was to improve the solubility of vortioxetine by crystal engineering principles. In this paper, three C2-C4 straight-chain dicarboxylic acid salt hydrates of vortioxetine (VOT-OA, VOT-MA-H2O, and VOT-SUA-H2O, VOT = vortioxetine,
Lei Gao, Xian-Rui Zhang, Shao-Ping Yang, Juan-Juan Liu, Chao-Jie Chen   +4 more
doaj   +1 more source

Peer review of the pesticide risk assessment of the active substance Straight Chain Lepidopteran Pheromones (SCLPs). [PDF]

EFSA J, 2021
European Food Safety Authority (EFSA), Alvarez F, Anastassiadou M, Arena M, Auteri D, Brancato A, Bura L, Carrasco Cabrera L, Castoldi AF, Chaideftou E, Chiusolo A, Colagiorgi A, Colas M, Crivellente F, De Lentdecker C, Egsmose M, Fait G, Greco L, Ippolito A, Istace F, Jarrah S, Kardassi D, Kienzler A, Leuschner R, Lava R, Alberto L, Lythgo C, Magrans O, Mangas I, Miron I, Molnar T, Padovani L, Parra Morte JM, Pedersen R, Reich H, Santos M, Sharp R, Szentes C, Terron A, Tiramani M, Vagenende B, Villamar-Bouza L.   +41 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

High efficient shape coding based on the representation of contour and chain code

Tongxin xuebao, 2014
A high efficient lossless shape coding scheme was proposed based on the representation of contour and chain code. The object contours are firstly extracted and thinned to be single-pixel width.
Zhong-jie ZHU, Yu-e WANG, Gang-yi JIANG
doaj   +2 more sources

A Straight-Chain Alcohol Glycoside, with Smooth Muscle Relaxant Activity, from (Raspberry) Leaves

Natural Product Communications, 2007
A methanolic extract of Rubus idaeus leaves, when fractionated by column chromatography, yielded two distinct bands containing compounds that demonstrated in vitro , dose dependent, smooth muscle relaxant activity using transmurally-stimulated Guinea pig
Asmita V. Patel, Christopher G. Dacke, Gerald Blunden, Janne Rojas Vera   +3 more
doaj   +1 more source

Interrelationships between Fatty Acid Composition, Staphyloxanthin Content, Fluidity, and Carbon Flow in the Staphylococcus aureus Membrane

Molecules, 2018
Fatty acids play a major role in determining membrane biophysical properties. Staphylococcus aureus produces branched-chain fatty acids (BCFAs) and straight-chain saturated fatty acids (SCSFAs), and can directly incorporate exogenous SCSFAs and straight ...
Kiran B. Tiwari, Craig Gatto, Brian J. Wilkinson   +2 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Fatigue Damage of V-Lock Chain Ring Under Random Load

Polish Maritime Research, 2016
To study the influence of the random load on the V-lock chain ring for mining, the numerical simulation technology is used. The dynamic tension is obtained by using the dynamic model of the plough.
Zhang Qiang, Wang Haijian, Guo Tong
doaj   +1 more source