Results 51 to 60 of about 511,312 (269)

Effect of Annealing on Strain Rate Sensitivity of Metallic Glass under Nanoindentation

Metals, 2020
The influence of isothermal annealing on the strain rate sensitivity (SRS) of a Zr-based bulk metallic glass (BMG) was investigated by nanoindentation. A more positive SRS is observed with a decrease in the content of the free volume (FV) of the sample ...
Mingcan Li
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The effect of strain rate sensitivity on the prediction of the formability of advanced high strength steels [PDF]

MATEC Web of Conferences
This paper analyzes the effect of strain rate sensitivity on the prediction of formability of advanced high-strength steels (AHSS). Three conventional dual-phase (DP) steels, 590DP, 980DP and 1180DP, and two third-generation AHSS grades with ultimate ...
Butuc Marilena C., Chezan Toni, Vincze Gabriela   +2 more
doaj   +1 more source

Notch and strain rate sensitivity of non-crimp fabric composites

Composites Science and Technology, 2009
The notch and strain rate sensitivity of noncrimp glass fibre/vinyl-ester laminates subjected to uniaxial tensile loads has been investigated experimentally.
Kazemahvazi, S., Zenkert, D., Burman, M.
openaire   +6 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Strain rate sensitivity metrics of PSU and PPSU high-performance polymers in extrusion-based additive manufacturing

Results in Engineering
High-performance polymers (HPPs), combined with material extrusion (MEX) additive manufacturing (AM), compile a powerful manufacturing system, suitable to meet the challenges of demanding industries. Their ability to undergo high strain rates is not well
Nectarios Vidakis, Markos Petousis, Nikolaos Mountakis, Maria Spyridaki, Ioannis Valsamos, Emmanuel Kymakis   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The strain-rate effect of engineering materials and its unified model

Latin American Journal of Solids and Structures
The test data of metals, brittle materials and polymers in high, medium and low strain-rate range were summarized. It was found that the dynamic strength or yield stress of these materials was not sensitive to strain-rate in the low and high strain-rate ...
YU Shui-sheng, LU Yu-bin, CAI Yong
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source