Results 51 to 60 of about 991,523 (306)

Piezoresistor-Embedded Multifunctional Magnetic Microactuators for Implantable Self-Clearing Catheter [PDF]

, 2019
Indwelling catheters are used widely in medicine to treat various chronic medical conditions. However, chronic implantation of catheters often leads to a premature failure due to biofilm accumulation.
Bentley, R. Timothy, Lee, Albert, Lee, Hyowon, Yang, Qi   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The NANOGrav 11 yr Data Set: Limits on Gravitational Wave Memory [PDF]

, 2020
The mergers of supermassive black hole binaries (SMBHBs) promise to be incredible sources of gravitational waves (GWs). While the oscillatory part of the merger gravitational waveform will be outside the frequency sensitivity range of pulsar timing ...
Aggarwal, K., Lazio, T. J. W., Simon, J.
core   +1 more source

Identification of non-homogeneous stress fields in dynamic experiments with a non parametric method [PDF]

, 2010
International audienceStress and strain fields are generally assumed homogeneous in high strain rate experiments. Therefore, only mean stress and strain are measured. However, this assumption is not valid for soft materials and/or very high strain rates.
Aloui, Souheila, Othman, Ramzi, Poitou, Arnaud   +2 more
core   +4 more sources

Study on the Dynamic Mechanical Behavior of 2D C/SiC Composites at Medium Strain Rates

Aerospace
Two-dimensional C/SiC are promising candidates for use in high-temperature structures in aeroengines and thermal protection systems in the aerospace industry, which will be subjected to loads in various directions during service.
Xinyue Zhang, Chao Zhang, Xiaochuan Liu, Chunyu Bai, Xulong Xi, Xiaocheng Li   +5 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Progressive Crushing of Polymer Matrix Composite Tubular Structures: Review [PDF]

, 2017
The present paper reviews crushing process of fibre-reinforced polymer (FRPs) composites tubular structures. Working with anisotropic material requires consideration of specific parameter definition in order to tailor a well-engineered composite ...
Ghasemnejad, Hessammaddin, Rabiee, Ali
core   +1 more source

Effects of the Strain Rate Sensitivity and Strain Hardening on the Saturated Impulse of Plates

Latin American Journal of Solids and Structures
This paper studies the stiffening effects of the material strain rate sensitivity and strain hardening on the saturated impulse of elastic, perfectly plastic plates.
Ling Zhu, Xu He, F. L. Chen, Xueyu Bai
doaj   +1 more source