Results 61 to 70 of about 512,401 (269)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of the strain rate in compression of electrodeposited gold micro-pillars toward the design of MEMS components

Micro and Nano Engineering
In this study, the strain rate dependence in yield strengths of electrodeposited gold micro-pillars is evaluated for the design of movable components in MEMS devices. The micro-pillars are fabricated from electrodeposited gold by focused ion beam system.
Shota Kanno, Taro Omura, Jhen-Yang Wu, Tomoyuki Kurioka, Chun-Yi Chen, Parthojit Chakraborty, Katsuyuki Machida, Hiroyuki Ito, Yoshihiro Miyake, Masato Sone, Tso-Fu Mark Chang   +10 more
doaj   +1 more source

Nanoindentation creep behavior of Cu–Zr metallic glass films

Materials Research Letters, 2018
The size-dependent hardness, strain-rate sensitivity (SRS) and shear transformation zone (STZ) volume of co-sputtered Cu–Zr metallic glass films with film thickness h spanning from 1000 to 3000 nm were systematically investigated by nanoindentation creep
Yaqiang Wang, Jinyu Zhang, Kai Wu, Gang Liu, Daniel Kiener, Jun Sun   +5 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Compressive behavior and deformation kinetics of ultrafine grained aluminum processed by equal channel angular pressing

International Journal of Smart and Nano Materials, 2017
In the present work, the uniaxial compressive mechanical proper\ties of ultrafine grained (UFG) aluminum produced by equal channel angular pressing method were investigated experimentally over a wide temperatures ranging from 77 to 473 K under both quasi-
Jin Su, Zhong-bin Tang, Cun-xian Wang, Tian Ye, Tao Suo, Yu-long Li   +5 more
doaj   +1 more source

Rate Dependence of the Compressive Response of Ti Foams

Metals, 2012
Titanium foams of relative density ranging from 0.3 to 0.9 were produced by titanium powder sintering procedures and tested in uniaxial compression at strain rates ranging from 0.01 to 2,000 s−1.
Nik Petrinic, Vito L. Tagarielli, Petros Siegkas, Louis-Philippe Lefebvre   +3 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Effect of element Ce on the strain rate sensitivity of Mg-Zn-Zr alloy

Journal of Magnesium and Alloys
Investigations into the strain rate sensitivity of magnesium (Mg) alloys represent a current research focus in materials science. However, most studies have examined strain rate sensitivity in single alloy, lacking systematic comparisons between ...
Chenkun Xu, Zhi Wang, Le Zhou, Feng Wang, Ziqi Wei, Pingli Mao   +5 more
doaj   +1 more source