Results 51 to 60 of about 5,416,454 (300)

Myocardial and Vascular Involvement in Patients with Takayasu Arteritis: A Cardiovascular MRI Study

open access: yesDiagnostics, 2023
We aimed to explore the cardiovascular magnetic resonance (CMR) of Takayasu arteritis (TA) and its cardiovascular complications. CMR was conducted on 37 TA patients and 28 healthy individuals.
Simin Almasi   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Advancing FRAP for cell studies: Where there is a new method, there is a new field

open access: yesJournal of Biomechanical Science and Engineering, 2023
Intracellular proteins are continuously replaced over time by chemical reaction called molecular turnover. Fluorescence recovery after photobleaching (FRAP) is a powerful technique to evaluate the turnover in living cells. In short-term FRAP measurements,
Takumi SAITO, Shinji DEGUCHI
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Diversity and Bioactive Potential of Actinobacteria from Unexplored Regions of Western Ghats, India

open access: yesMicroorganisms, 2020
The search for novel bioactive metabolites continues to be of much importance around the world for pharmaceutical, agricultural, and industrial applications.
Saket Siddharth   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The effects of strain, reproductive condition, and strain of placenta donor on placentophagia in nonpregnant mice [PDF]

open access: yes, 1973
The effects on placentophagia of strain, reproductive condition, and strain of placenta donor were observed in nonpregnant mice. Mice of the C57BL/6By and BALB/cBy strains were exposed to placentas of either strain after either no previous parturitional ...
Kristal, Dr. Mark B.   +1 more
core   +1 more source

Strain and Strain Rate Echocardiography

open access: yesMethodist DeBakey Cardiovascular Journal, 2006
Myocardial function is eventually determined by the shortening and lengthening of myocardium, i.e., myocardial deformation or strain. The exact and direct measure of myocardial deformation has been dependent on the in vitro analysis of myocardial length.
Jianwen Wang, Sherif F. Nagueh
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

STRING data mining of GWAS data in canine hereditary pigment-associated deafness

open access: yesVeterinary and Animal Science, 2020
Most canine deafness is linked to white pigmentation caused by the piebald locus, shown to be the gene MITF (melanocyte inducing transcription factor), but studies have failed to identify a deafness cause.
Maria Kelly-Smith, George M. Strain
doaj   +1 more source

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