Results 71 to 80 of about 1,263,376 (271)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Piezoresistive diamond-like carbon micro strain gauges

, 2022
Hydrogenated (a-C:H) and hydrogen-free (a-C) amorphous diamond-like carbon (DLC) strain gauges have been successfully integrated on micromachined silicon bossmembrane force sensors.
Doering, L., Biehl, S., Peiner, E., Lüthje, H., Tibrewala, A., Bandorf, R.   +5 more
core   +1 more source

Piezoresitive diamond-like carbon micro strain gauges

, 2022
S.1651-1656Hydrogenated (a-C:H) and hydrogen-free (a-C) amorphous diamond-like carbon (DLC) strain gauges have been successfully integrated on micromachined silicon bossmembrane force sensors.
Doering, L., Biehl, S., Peiner, E., Lüthje, H., Tibrewala, A., Bandorf, R.   +5 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Polynomial Identification of Strain Gauge Thermal Output...

Promet (Zagreb), 2002
Strain gauges are used in different areas, especially in thedesign and development of new technical constructions andmode/testing. Also, strain gauges are inc01porated in the functionalpart of many instruments and devices.
Igor Vujović, Ivica Kuzmanić, Zlatan Kulenović   +2 more
doaj   +1 more source

Application of Strain Gauges in Measurements of Strain Distribution in Complex Objects [PDF]

, 2014
This article presents an application of strain gauges in measurements of strain which occurs in charge air cooler during the thermal cycle test. The work shows the main idea of measuring system based on strain gauges and important aspects that should be ...
Tutak, P.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Monitoring fracture healing with strain gauges: the effect on strain values of strain gauge location on the pin circumference

, 1995
In an attempt to establish some principles for the use of strain gauges in monitoring fracture healing, four strain gauges were fastened onto the most proximal pin of a Shearer external fixator applied to a hardwood fracture model.
O.O.A. Oni, C. Soutis, Oni, O. O A, Capper, M., M. Capper, Soutis, C.; id_orcid   +5 more
core   +4 more sources

USAGE OF STRAIN GAUGES IN CONSTRUCTION [PDF]

, 2019
This article discusses the use of strain gauges in determining the magnitude of the voltage arising in building structures, as well as their use in the dosing and weighing processes of components of reinforced concrete products.
Sirojiddinov, U.
core