Results 81 to 90 of about 76,097 (293)

Kondo insulator SmB6 under strain: surface dominated conduction near room temperature [PDF]

, 2017
SmB6 is a strongly correlated mixed-valence Kondo insulator with a newly discovered surface state, proposed to be of non-trivial topological origin. However, the surface state dominates electrical conduction only below T* ~ 4 K limiting its scientific ...
Dzero, M., Fisk, Z., Galitski, V. M., Stern, A., Xia, J.   +4 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

The Effects of Air and Underwater Blast on Composite Sandwich Panels and Tubular Laminate Structures

, 2012
The resistance of glass-fibre reinforced polymer (GFRP) sandwich panels and laminate tubes to blast in air and underwater environments has been studied.
A Neuberger, A Neuberger, EH Wang, H. Arora, J LeBlanc, J. P. Dear, MS Hoo Fatt, P. A. Hooper, R Rajendran, SA Tekalur, SA Tekalur, SA Tekalur, VS Deshpande, YW Kwon   +13 more
core   +1 more source

Experimental and analytical assessment of ductility in lightly reinforced concrete members [PDF]

, 2010
This is the post-print version of the final paper published in Engineering Structures. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting,
A.Y. Elghazouli, B.A. Izzuddin, Bailey, Bailey, Cashell, Elghazouli, Elghazouli, Elghazouli, Gillie, Huang, Izzuddin, Izzuddin, Izzuddin, K.A. Cashell, Lim, Omer, O’Connor, Scott, Wang   +18 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Polynomial Identification of Strain Gauge Thermal Output...

Promet (Zagreb), 2002
Strain gauges are used in different areas, especially in thedesign and development of new technical constructions andmode/testing. Also, strain gauges are inc01porated in the functionalpart of many instruments and devices.
Igor Vujović, Ivica Kuzmanić, Zlatan Kulenović   +2 more
doaj   +1 more source

Selected Problems of Determining Critical Loads in Sructures with Stable Post-Critical Behaviour. [PDF]

, 2016
This paper presents selected cases of inapplicability of theory based methods of determining critical loads in thin – walled, composite tubes. 8th layered composite tubes with square cross-section were being subjected to static compression and in order ...
Czapski, Paweł, Kubiak, Tomasz
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The high strain-rate behaviour of three molecular weights of polyethylene examined with a magnesium alloy split-Hopkinson pressure bar

, 2013
A traditional split-Hopkinson pressure bar system has been modified by the addition of ZK60A magnesium alloy pressure bars in order to increase the resolution of data when examining specimens of low-density, high-density and ultra-high molecular weight ...
Hughes, Foz, Prudom, Andrew, Swallowe, Gerry   +2 more
core   +1 more source