Results 51 to 60 of about 829,168 (336)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Perspective on hetero-deformation induced (HDI) hardening and back stress
Materials Research Letters, 2019 Heterostructured materials have been reported as a new class of materials with superior mechanical properties, which was attributed to the development of back stress.
Yuntian Zhu, Xiaolei Wu
doaj +1 more source
The Green tensor of Mindlin's anisotropic first strain gradient elasticity
, 2019 We derive the Green tensor of Mindlin's anisotropic first strain gradient elasticity. The Green tensor is valid for arbitrary anisotropic materials, with up to 21 elastic constants and 171 gradient elastic constants in the general case of triclinic media.
Admal, Nikhil Chandra +2 more
core +1 more source
Piezoelectric mimicry of flexoelectricity [PDF]
, 2018 The origin of "giant" flexoelectricity, orders of magnitude larger than theoretically predicted, yet frequently observed, is under intense scrutiny. There is mounting evidence correlating giant flexoelectric-like effects with parasitic piezoelectricity ...
Abdollahi, Amir +2 more
core +4 more sources
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Spectral alignment of single-photon emitters in diamond using strain gradient
, 2018 Solid-state single-photon emitters are attractive for realization of integrated quantum systems due to their experimental convenience and scalability. Unfortunately, however, their complex mesoscopic environments cause photons from different emitters to ...
Bielejec, Edward +7 more
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Heterogeneous materials: a new class of materials with unprecedented mechanical properties
Materials Research Letters, 2017 Here we present a perspective on heterogeneous materials, a new class of materials possessing superior combinations of strength and ductility that are not accessible to their homogeneous counterparts.
Xiaolei Wu, Yuntian Zhu
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source