Results 51 to 60 of about 49,441 (301)

The Mathematical and Physical Inconsistencies of Strain-Gradient Theories

Mathematics
In this paper, we examine the inherent mathematical and physical inconsistencies of strain-gradient theories. It is shown that strain gradients are not proper measures of deformation, because their corresponding energetically conjugate stresses are non-physical and cannot represent the state of internal stresses in the continuum.
Ali R. Hadjesfandiari, Gary F. Dargush
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

One-Dimensional Large-Strain Nonlinear Consolidation of Overconsolidated Clays with a Threshold Hydraulic Gradient

Advances in Civil Engineering, 2018
The existence of the threshold hydraulic gradient in clays under a low hydraulic gradient has been recognized by many studies. Meanwhile, most nature clays to some extent exist in an overconsolidated state more or less.
Chuanxun Li, Jinyang Xiao, Yang Yang, Wenbing Wu   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Four simplified gradient elasticity models for the simulation of dispersive wave propagation

, 2008
Gradient elasticity theories can be used to simulate dispersive wave propagation as it occurs in heterogeneous materials. Compared to the second-order partial differential equations of classical elasticity, in its most general format gradient elasticity ...
Pichugin, AV, Bennett, T, Metrikine, A., Askes, H., Bennett, T., Pichugin, A., Metrikine, AV, Askes, H   +7 more
core   +1 more source

A Brief Note on the Nix–Gao Strain Gradient Plasticity Theory

Metals, 2018
The mathematical nature of the flow rule for the strain gradient plasticity theory proposed by Nix and Gao (W.D. Nix and H. Gao, J Mech Phys Solids 46(3), 411(1998)) is discussed based on the paradigm developed by Gurtin and Anand (M.E.
A. S. Borokinni, Dabiao Liu
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Steady-state crack growth and fracture work based on the theory of mechanism-based strain gradient plasticity

, 2003
Mode I steady-state crack growth is analyzed under plane strain conditions in small scale yielding. The elastic-plastic solid is characterized by the mechanism-based strain gradient (MSG) plasticity theory [J. Mech. Phys. Solids 47 (1999) 1239, J.
Hwang KC, Qiu X, 魏悦广, Wei, Y (reprint author), Chinese Acad Sci, Inst Mech, LNM, Beijing 100080, Peoples R China.   +3 more
core   +1 more source

Gradient flows as a selection procedure for equilibria of nonconvex energies [PDF]

, 2006
For atomistic material models, global minimization gives the wrong qualitative behavior; a theory of equilibrium solutions needs to be defined in different terms.
Ortner, Christoph
core   +1 more source