Results 31 to 40 of about 600,912 (282)

Hardening effects on formability limit prediction based on gurson-type damage models and bifurcation analysis [PDF]

open access: yes, 2017
In this work, ductility limits of metallic materials, associated with the occurrence of strain localization, are predicted using the GTN damage model coupled with bifurcation theory.
Abed-Meraim, F., Chalal, H.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Analysis of strain localization with a nonlocal plasticity model [PDF]

open access: yes, 2017
In the present paper a nonlocal plasticity model is described, intended to reproduce the mechanical behaviour of stiff fine-grained soils, including the objective simulation of strain localization; the phenomenon of accumulation of deformations in narrow ...
Gens Solé, Antonio   +3 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Localization in inelastic rate dependent shearing deformations

open access: yes, 2016
Metals deformed at high strain rates can exhibit failure through formation of shear bands, a phenomenon often attributed to Hadamard instability and localization of the strain into an emerging coherent structure.
Katsaounis, Theodoros   +2 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Melt‐Supported Strain Localization at Eclogite‐Facies Conditions Triggered by Syn‐Metamorphic Strength Inversion

open access: yesGeochemistry, Geophysics, Geosystems
In convergent high‐pressure settings dominated by dry mafic rocks, strain has been proposed to be predominantly localized in eclogite. However, the processes initiating strain localization, accommodating strain and rheological consequences remain to be ...
Anna Rogowitz   +4 more
doaj   +1 more source

Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. [PDF]

open access: yes, 2014
The exocyst serves to tether secretory vesicles to cortical sites specified by polarity determinants, in preparation for fusion with the plasma membrane.
Liu, Dongmei, Novick, Peter
core   +1 more source

Nonlinear Spatial Localized Strain Waves [PDF]

open access: yesEPJ Web of Conferences, 2018
A possible way of study of single waves in solids is discussed. The soliton is one of these waves without shape and parameters varying. Soliton deformation parameters are connected with the elastic moduli of the third order that allows defining values of these moduli by means of the measured solitondeformation parameters in various type waveguides made
Erofeev Vladimir I.   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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