Results 41 to 50 of about 7,742,171 (287)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Two optical full-field strain measurement techniques, Digital Image Correlation and the Grid Method, are applied to characterise the strain-rate dependent constitutive behaviour of composite materials.
Longana, M.L.
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
STRAIN/STRAIN RATE ECHOCARDIOGRAPHY
The characterization of local myocardial deformation, for both local radial and longitudinal function, could be important in heart diseases. Strain and strain rate echocardiography derived tissue Doppler imaging is a new clinical approach to quantifying ...
Enbiya Aksakal
doaj
Strain Hardening Exponent and Strain Rate Sensitivity Exponent of Cast AZ31B Magnesium Alloy
The flow curves of as-cast AZ31B magnesium alloy during high temperature deformation were obtained with a thermal compression test, and the effects of deformation amount, grain size, strain rate, and deformation temperature on the flow stress, strain ...
Yanchun Zhu +5 more
doaj +1 more source
Rheometer Strain and Strain-Rate Errors [PDF]
We have found systematic errors which can affect measured rheological properties in the instrumentation of two commercial rheometers. Users of commercial instrumentation should establish the extent to which these and similar errors may exist in their systems.
Giles, D.W., Denn, M.M.
openaire +2 more sources
Left ventricular strain and strain rate in a general population [PDF]
Strain and strain rate (SR) are measures of deformation that reflect left ventricular (LV) function. To our knowledge, no previous study described these indexes in a general population. We therefore described peak-systolic strain and SR of the LV in the general population and derived diagnostic thresholds for these measurements in a healthy subgroup.In
Tatiana, Kuznetsova +7 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

