Results 111 to 120 of about 19,178,039 (347)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Loading rate dependence of permeability evolution in porous aeolian sandstones [PDF]

open access: yes, 2004
Mechanical properties of rocks are characterized by their notable dependence on the applied deformation rate. However, little is known about the strain rate dependence of fluid flow properties since most laboratory tests are conducted using a single ...
Ira O. Ojala   +8 more
core   +1 more source

Kinematic and isotropic strain hardening in copper with highly aligned nanoscale twins

open access: yesMaterials Research Letters, 2018
The kinematic and isotropic strain hardening was investigated in columnar-grained copper with preferentially oriented nanoscale twins deformed at two different strain rates of 5 × 10−5 and 5 × 10−3 s−1.
Hao Wang, Zesheng You, Lei Lu
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

STRAIN-RATE EFFECTS [PDF]

open access: yes, 1970
Klahn, Dale   +2 more
openaire   +4 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Modelling, identification and application of phenomenological constitutive laws over a large strain rate and temperature range [PDF]

open access: yes, 2013
A review of the different phenomenological thermo-viscoplastic constitutive models often applied to forging and machining processes is presented. Several of the most common models have been identified using a large experimental database (Hor et al., 2013)
GERMAIN, Guénaël   +3 more
core   +1 more source

Quasi-Static Loading Responses and Constitutive Modeling of Al–Si–Mg alloy

open access: yesMetals, 2018
The flow behavior of the Al–Si–Mg alloy under uniaxial compression loading was investigated at different strain rates (10−3 s−1, 10−2 s−1,10−1 s−1, 100 s−1) at a wide range of temperatures (573 K, 623
Zhenglong Liang, Qi Zhang
doaj   +1 more source

Experimental study on granite and the determination of its true strain-rate effect

open access: yes, 2015
To accurately determine the true strain-rate effect of granite in split Hopkinson pressure bar (SHPB) tests, systematic experimental studies from quasi-static to dynamic loading on the same batch of granite samples is required.
Yong Cai, Shui-Sheng Yu, Yu-Bin Lu
semanticscholar   +1 more source

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