Results 61 to 70 of about 512,239 (311)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Slip transfer across phase boundaries in dual phase titanium alloys and the effect on strain rate sensitivity

, 2018
Dislocation transmission through α/β phase boundaries in titanium alloys is studied using integrated crystal plasticity (CP) and discrete dislocation plasticity (DDP) modelling techniques, combined with experimental micro-pillar compression test results.
Zebang Zheng, S. Waheed, D. Balint, F. Dunne   +3 more
semanticscholar   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Effect of element Ce on the strain rate sensitivity of Mg-Zn-Zr alloy

Journal of Magnesium and Alloys
Investigations into the strain rate sensitivity of magnesium (Mg) alloys represent a current research focus in materials science. However, most studies have examined strain rate sensitivity in single alloy, lacking systematic comparisons between ...
Chenkun Xu, Zhi Wang, Le Zhou, Feng Wang, Ziqi Wei, Pingli Mao   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Effects of the strain rate in compression of electrodeposited gold micro-pillars toward the design of MEMS components

Micro and Nano Engineering
In this study, the strain rate dependence in yield strengths of electrodeposited gold micro-pillars is evaluated for the design of movable components in MEMS devices. The micro-pillars are fabricated from electrodeposited gold by focused ion beam system.
Shota Kanno, Taro Omura, Jhen-Yang Wu, Tomoyuki Kurioka, Chun-Yi Chen, Parthojit Chakraborty, Katsuyuki Machida, Hiroyuki Ito, Yoshihiro Miyake, Masato Sone, Tso-Fu Mark Chang   +10 more
doaj   +1 more source

Rate Dependence of the Compressive Response of Ti Foams

Metals, 2012
Titanium foams of relative density ranging from 0.3 to 0.9 were produced by titanium powder sintering procedures and tested in uniaxial compression at strain rates ranging from 0.01 to 2,000 s−1.
Nik Petrinic, Vito L. Tagarielli, Petros Siegkas, Louis-Philippe Lefebvre   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Interactions of negative strain rate sensitivity, martensite transformation, and dynamic strain aging in 3rd generation advanced high-strength steels

Materials Science & Engineering: A, 2019
Medium Mn transformation-induced plasticity (TRIP) steels, a subgroup of third generation advanced high-strength steels (AHSS), often present a combination of both dynamic strain aging (DSA) and TRIP. It has been previously shown that TRIP coincides with
M. Callahan, A. Perlade, J. Schmitt
semanticscholar   +1 more source

Compressive behavior and deformation kinetics of ultrafine grained aluminum processed by equal channel angular pressing

International Journal of Smart and Nano Materials, 2017
In the present work, the uniaxial compressive mechanical proper\ties of ultrafine grained (UFG) aluminum produced by equal channel angular pressing method were investigated experimentally over a wide temperatures ranging from 77 to 473 K under both quasi-
Jin Su, Zhong-bin Tang, Cun-xian Wang, Tian Ye, Tao Suo, Yu-long Li   +5 more
doaj   +1 more source