Results 101 to 110 of about 1,885,448 (317)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Impact of ecophysiological factors on biocontrol of aflatoxin contamination of maize by atoxigenic aspergillus flavus strains [PDF]
, 2013 This study has (a) evaluated the biodiversity in toxigenic mycobiota associated with maize from subsistence farmers’ stores in five climatic regions of Lesotho in two seasons, (b) compared the effect of ecophysiological factors on interactions between ...
Mohale, Sejakhosi Alexis
core
The behaviour of some tobacco necrosis virus strains in plants
, 1963 Strains of tobacco necrosis virus (TNV) differed in their behaviour when inoculated to French bean leaves which were exposed to different temperatures. At 20° strains A and D increased much faster than strain B.
Babos, P., Kassanis, B.
core +1 more source
Major physical characteristics of Rochelle salt: the role of thermal strains
Condensed Matter Physics, 2012 We compare the results for the related to the shear strain ε4 physical characteristics of Rochelle salt obtained within the recently developed modified two-sublattice Mitsui model that takes into account the strain ε4 and the diagonal components of the ...
A.P. Moina
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2010 PhDApproximately one-third of the global population is infected with tuberculosis causing approximately 1.7 million deaths. Currently, the BCG vaccine is used to protect against TB, but it cannot prevent primary infection or reactivation of latent ...
Velji, Preya
core
, 2014 Glycosylphosphatidylinositols (GPIs) from several protozoan parasites are thought to elicit a detrimental stimulation of the host innate immune system aside their main function to anchor surface proteins.
Ricardo T. Gazzinelli (164680) +43 more
core +1 more source
ROTAVIRUS INFECTION. HOW TO REALLY PROTECT CHILDREN FROM SEVERE GASTROENTERITIS?
Педиатрическая фармакология, 2013 According to the statistics of the recent 5 years, the share of rotavirus gastroenterites is 44-47% of all acute intestinal infections in children under 5 years of age in the Russian Federation. Up to 5% of mortality rate in children under 5 years of age
T. A. Grechukha +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source