Results 101 to 110 of about 2,922,919 (313)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Trypanosoma cruzi: Genomic Diversity and Structure

open access: yesPathogens
Trypanosoma cruzi is the causative agent of Chagas disease, a neglected tropical disease, and one of the most important parasitic diseases worldwide. The first genome of T.
Alfonso Herreros-Cabello   +3 more
doaj   +1 more source

Methicillin-resistant Staphylococcus aureus (MRSA) ST398 associated with clinical and subclinical mastitis in Belgian cows [PDF]

open access: yes, 2010
Methicillin-resistant Staphylococcus aureus (MRSA) is infrequently reported in mastitis. Yet, as in many other countries, the prevalence of methicillin resistance among S. aureus from mastitis is currently unknown in Belgium.
Adriaensen, Connie   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Total antibodies and neutralizing ability of convalescent sera against three different strains of SARS-CoV-2

open access: yesВопросы вирусологии
The aim of the study was to assess the level of humoral immunity to SARS-CoV-2 in COVID-19 convalescents. Materials and methods. We used ELISA for antibody quantitation, microneutralization test using three SARS-CoV-2 strains for neutralizing activity
Natalia V. Palyanova   +6 more
doaj   +1 more source

Long-range order and short-range disorder in Saccharomyces cerevisiae biofilm

open access: yesEngineering Biology, 2019
Biofilm, a colony forming cooperative response of microorganisms under environmental stress, is a major concern for food safety, water safety and drug resistance. Most current works focus on controlling biofilm growth by targeting single genes. Here, the
Vincent Piras   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

LOAD TESTING OF THE HERCEGOVINA BRIDGE

open access: yese-Zbornik. Elektronički Zbornik Radova Građevinskog Fakulteta
The paper presents static and dynamic load testing of the Hercegovina bridge over the Neretva River. In addition to presenting the basic structural elements of the bridge, the paper briefly describes the testing method, and provides the basic ...
Mladen Kustura   +2 more
doaj   +1 more source

CARDIAC STRAIN. [PDF]

open access: yesThe Lancet, 1910
n ...
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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