Results 51 to 60 of about 1,885,448 (317)

„Man rennt, man kommt gar nicht zur Ruhe“

open access: yesMonitor Versorgungsforschung, 2021
Die Covid-19-Pandemie hat die allgemein schon hohe Belastungssituation in der Pflege nochmals verschärft. Erste Studien zeigen bereits stressbedingte psychische Symptome infolge von Mehrbelastungen.
Thomas Sebastian Müller BA (cand.)   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

In Vitro Evaluation of Adhesion Capacity, Hydrophobicity, and Auto-Aggregation of Newly Isolated Potential Probiotic Strains

open access: yes, 2019
We isolated several strains of human and animal origin, focusing on the genera Lactobacillus and Bifidobacterium. Samples of cow colostrum, feces and saliva of calves and piglets, and infant feces were acquired, bacterial strains were isolated and ...
Iveta Hynstova   +2 more
core   +1 more source

ANTIGENIC AND PROTECTIVE PROPERTIES OF EXPERIMENTAL ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX AND GOAT POX

open access: yesВетеринария сегодня, 2018
Studies have been carried on antigenic and protective activity of the experimental associated vaccine containing, in the field vaccination dose, antigens of the attenuated ARRIAH strain of the sheep pox virus and ARRIAH 2003 strain of the goat pox virus ...
A. V. Konstantinov   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Preclinical and clinical trials of a new Ukrainian inactivated vaccine against actinobacillary pleuropneumonia in pigs

open access: yesTheoretical and Applied Veterinary Medicine, 2023
Respiratory diseases are a problem for the pig industry in all countries engaged in pig breeding and industrial pork production. Actinobacillary pleuropneumonia of pigs is one of the most common bacterial respiratory diseases of pigs, which is recorded ...
M. M. Derevyanko, O. E. Ayshpur
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Taxonomic and phylogenetic evaluation of Limnothrix strains (Oscillatoriales, Cyanobacteria) by adding Limnothrix planktonica strains isolated from central China [PDF]

open access: yes, 2012
Six Limnothrix strains, isolated for the first time from a shallow eutrophic lake in central China, were taxonomically and phylogenetically evaluated by investigating their polyphasic characteristics, including morphological features, cellular ...
Li, Xiaochuang   +5 more
core   +1 more source

Chracterization on two isolates of potato virus Y and ultrastructural alteration of host cells infected with the two isolates

open access: yes浙江大学学报. 农业与生命科学版, 2002
The present paper gives detailed description about the differences of two isolates of potato virus Y (PVY) in biological properties, morphology of purified virus particle, serological relationship and the ultrastructural alterations in infected tobacco ...
GUO Xing-qi   +4 more
doaj   +1 more source

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