Results 21 to 30 of about 699,160 (266)

Reconstituting the 4-Strand DNA Strand Exchange [PDF]

, 2018
Proteins of the Rad51 family play a key role in homologous recombination by carrying out DNA strand exchange. Here, we present the methodology and the protocols for the 4-strand exchange between gapped circular DNA and homologous linear duplex DNA promoted by human Rad51 and Escherichia coli RecA orthologs.
Olga M, Mazina, Alexander V, Mazin
openaire   +2 more sources

Synagelides Strand in Bosenberg & Strand 1906

, 2020
Key to the male Synagelides of Sri Lanka 1. MA present.......................................................................................... 2 - MA absent........................................................................................... 3 2. RTA bifurcated, tips unequal...................................................
Kanesharatnam, Nilani, Benjamin, Suresh P.   +1 more
openaire   +4 more sources

Transfer Lengths in Pretensioned Concrete Measured Using Various Sensing Technologies

International Journal of Concrete Structures and Materials, 2019
Although pretensioned concrete structures have increasingly been used worldwide, a number of design issues need to be addressed to further improve the structural performance.
Se-Jin Jeon, Ho Shin, Sang-Hyun Kim, Sung Yong Park, Jun-Mo Yang   +4 more
doaj   +1 more source

An unexpected case of disseminated mucormycosis following pacemaker placement and brief course of oral corticosteroids

IDCases, 2022
Mucormycosis is a rare opportunistic fungal infection with a high degree of morbidity and mortality. It classically presents with rapidly progressing, necrotic rhinocerebral mucocutaneous lesions in the setting of an immunocompromised host, especially ...
Chadley Froes, Matthew Gellatly, Brian Watson   +2 more
doaj   +1 more source

Control of the transmission length in the prestressed hollow-core slabs using values of the strand end slip

Budownictwo i Architektura, 2013
It is shown [1] that even though the production of precast pre-tensioned concrete elements started more than 50 years ago, no one has ever succeeded in determining the real transmission length or in obtaining adequate measures to control it, due to the ...
Victor Tur, Stanisław Fic
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Landscape of clinically actionable mutations in breast cancer ‘A cohort study’

Translational Oncology, 2021
Breast cancer (BC) is a heterogeneous disease. Numerous chemotherapeutic agents are available for early stage or advanced/metastatic breast cancer to provide maximum benefit with minimum side effects.
Mithua Ghosh, Radheshyam Naik, Sheela Mysore Lingaraju, Sridhar Papaiah Susheela, Shekar Patil, Gopinath Kodaganur Srinivasachar, Satheesh Chiradoni Thungappa, Krithika Murugan, Srinivas Belagutty Jayappa, Somorat Bhattacharjee, Nalini Rao, Mahesh Bandimegal, Roopesh Krishnappa, Shashidhara Haragadde Poppareddy, Krishna Chennagiri Raghavendrachar, Yogesh Shivakumar, Sunitha Nagesh, Ramya Kodandapani, Ashwini Rajan, Urvashi Bahadur, Pooja Agrawal, Veena Ramaswamy, Tejaswini Bangalore Nanjaiah, Sateesh Kunigal, Shanmukh Katragadda, Ashwini Manjunath, Amritanshu Ram, Basavalinga S. Ajaikumar   +27 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source