Results 41 to 50 of about 699,160 (266)
IDCases, 2022 We report a case of a 54-year-old immunocompetent female with cervical spine discitis and osteomyelitis secondary to Nocardia nova. Nocardia nova is overall an exceedingly rare cause of infectious diseases. In this case, the patient was admitted for neck
Larissa Check +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sensors, 2020 We present an initial experimental validation of a microwave tomography (MWT) prototype for brain stroke detection and classification using the distorted Born iterative method, two-step iterative shrinkage thresholding (DBIM-TwIST) algorithm.
Olympia Karadima +6 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Creating and moving nanoantenna cold spots anywhere
Light: Science & Applications, 2022 Cold spots are sub-wavelength regions which might emerge near a nanoantenna, should one or more components of some far-field illumination cancel out with scattered light.
Alex J. Vernon +1 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Intracerebral tuberculomas: A rare cause of seizure in an immunocompetent young male
IDCases, 2019 Central nervous system (CNS) involvement occurs in about 1% of all tuberculosis (TB) cases, classically presenting as a meningitis. Intracerebral tuberculomas are a much rarer manifestation.
Khiem Vu +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A decomposition of light’s spin angular momentum density
Light: Science & ApplicationsLight carries intrinsic spin angular momentum (SAM) when the electric or magnetic field vector rotates over time. A familiar vector equation calculates the direction of light’s SAM density using the right-hand rule with reference to the electric and ...
Alex J. Vernon +4 more
doaj +1 more source