Results 51 to 60 of about 1,815,704 (239)

European Strategic Autonomy and Small States' Security

, 2023
This book analyses whether the EU’s drift towards European strategic autonomy presents a challenge or a window of opportunity for its small member states to advance their security interests.

core   +2 more sources

India–South Korea Semiconductor Cooperation and Technological Strategic Autonomy

Panoply Journal
Semiconductors have moved from the domain of industrial policy to the center of geopolitical competition, and technological strategic autonomy has become the organizing ambition of states seeking to reduce dependence on concentrated supply chains.
Ronak Sagar
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pojęcie oraz techniczny wymiar autonomii strategicznej Unii Europejskiej

Politeja
THE CONCEPT AND TECHNICAL ASPECTS OF STRATEGIC AUTONOMY OF THE EUROPEAN UNION: THE EXAMPLE OF SPACE POLICY The author of the article addresses the issue of strategic autonomy of the European Union.
Bartosz Smolik
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Road to Strategic Autonomy: Reflections from the Russia-Ukraine War

De Europa
Since 2016, the European Union (EU)’s ambitions to become more autonomous from the US have sparked intensified debate. Academics hold contrasting perspectives on the EU’s potential for achieving strategic autonomy.
Matteo Mazziotti di Celso, Mattia Sguazzini   +1 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

CFSP and the EU’s Strategic Autonomy: Between Ambition and Reality Amid Global Instability [PDF]

Međunarodna politika
The article explores the development, challenges, and future prospects of the European Union’s Common Foreign and Security Policy (CFSP) in light of the evolving concept of EU strategic autonomy.
Marko Novaković, Mihajlo Vučić
doaj   +1 more source