Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Productivity growth and functional upgrading in foreign subsidiaries in the Slovenian manufacturing sector [PDF]
, 2005 The paper discusses the determinants of productivity growth in manufacturing foreign subsidiaries in Slovenia. Special attention is given to the impact of control pattern.
Jaklič, A +3 more
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Talent management in academia: the effect of discipline and context on recruitment [PDF]
, 2016 Although talent management is widely discussed in large for –profit organisations and multinationals, it has been little discussed in relation to higher education.
Paisey, Catriona, Paisey, Nicholas J.
core +2 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Strategic autonomy: A ‘quantum leap forward on’ European total defence?
European Journal of International SecurityIn the last decade, the idea of total defence – a whole-of-society approach integrating civilian and military capabilities – has gained renewed prominence in Europe, including within the European Union (EU).
Jana Wrange
doaj +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
The Road to Strategic Autonomy: Reflections from the Russia-Ukraine War
De EuropaSince 2016, the European Union (EU)’s ambitions to become more autonomous from the US have sparked intensified debate. Academics hold contrasting perspectives on the EU’s potential for achieving strategic autonomy.
Matteo Mazziotti di Celso +1 more
doaj +1 more source
Use Your Strategic Entrepreneurs to Build Your Strategic Partnerships [PDF]
, 2014 Internationalisation through strategic partnerships is a goal for many higher education institutions and their upper-level management teams. Yet for institutional objectives to truly flourish, they should get the most out of the various skills that ...
Berg Thomsen, Kristian +6 more
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Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Pojęcie oraz techniczny wymiar autonomii strategicznej Unii Europejskiej
PolitejaTHE CONCEPT AND TECHNICAL ASPECTS OF STRATEGIC AUTONOMY OF THE EUROPEAN UNION: THE EXAMPLE OF SPACE POLICY The author of the article addresses the issue of strategic autonomy of the European Union.
Bartosz Smolik
doaj +1 more source