Results 101 to 110 of about 268,044 (293)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Leveraging Data Analytics for Strategic Logistics Decision-Making

International Journal of Applied Research in Business and Management
The evolving landscape of global commerce has transformed logistics from a tactical function into a critical strategic lever. As supply chains grow increasingly complex and demand more responsiveness, organizations are turning to data analytics to ...
Pamela Zama Nomzaza
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prescriptive Model for the Strategic Decision-Making Processes from the Romanian Enterprises [PDF]

This paper proposes a prescriptive model for the strategic decision-making from the Romanian enterprises. Within the paper there will be described the phases implied in solving a strategic problem.
Razvan Stefanescu
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Process of Strategic Decision-Making in Libyan Commercial Banks

The thesis describes an exploration and analysis of the nature of strategic decision-making processes (SDMP) in Libyan Commercial Banks. The role of 'rationality‘, 'intuition‘ and 'political behaviour‘ in five strategic decisions of very high importance ...
Ftes, Nagah Abdulaziz M
core  

AI-driven Decision-Making Models for Strategic Management: A Comprehensive Framework for Organizational Excellence in the Digital Era

JISR on Computing
– The rapid development of artificial intelligence (AI) technologies has fundamentally transformed strategic decision-making processes in organizations worldwide. Traditional strategic management frameworks are increasingly being augmented or replaced by
Syed Ali Raza Naqvi, Syed Muhammad Hassan Naqvi, Adeel Ur Rehman, Baset Sayed   +3 more
doaj   +1 more source

Editorial: Affect and cognition in upper echelons' strategic decision making: Empirical and theoretical studies for advancing corporate governance. [PDF]

Front Psychol, 2022
Cristofaro M, Bao YJ, Chiu S, Hernández-Lara AB, Perez-Calero L.   +4 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Strategic Decision Making In Competitiveness Based Management

For companies on competitiveness based management process it is appropriate to use the advantages of strategic management. Strategy is one of the main and most complex functions of the business policy, especially if the issue is related to ...
Fedotova, Kristīne
core