Results 161 to 170 of about 1,539,111 (274)

Strategic Decision-Making In Turbulent Setting: Creating Strategic Momentum � [PDF]

decision ...
Aken, van J.E., Akkermans, H.A.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Application of the Analytical Hierarchy Process in the management of private ambulance care systems in three selected European countries: a strategic decision-making framework. [PDF]

Front Public Health
Rezaei J, Azouji R, Azouji M, Ghorbani H.   +3 more
europepmc   +1 more source

Correction to 'Strategic decision making about travel during disease outbreaks: a game theoretical approach'. [PDF]

J R Soc Interface, 2019
Zhao S, Bauch CT, He D.
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Trait reward sensitivity modulates connectivity with the temporoparietal junction and Anterior Insula during strategic decision making. [PDF]

Biol Psychol
Sazhin D, Wyngaarden JB, Dennison JB, Zaff O, Fareri D, McCloskey MS, Alloy LB, Jarcho JM, Smith DV.   +8 more
europepmc   +1 more source

Strategic decision making about travel during disease outbreaks: a game theoretical approach. [PDF]

J R Soc Interface, 2018
Zhao S, Bauch CT, He D.
europepmc   +1 more source

MULTI-CRITERIA ANALYSIS AS A TOOL FOR MUNICIPAL PROPERTY MANAGEMENT [PDF]

In most decision making situations more than one criterion is involved and, as a consequence, confusion can arise if there is no logical and well structured decision-making process in place.
Bogdan Ileanu, Daniela Constantin, Statty Statev, Stela Raleva, Zizi Goschin   +4 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The Effects of Pre-Response Before COVID-19 Outbreak on Strategic Decision Making

, 2020
Jung JH, Kim D, Jung IH.
europepmc   +2 more sources