Results 61 to 70 of about 124,177 (299)
Navigating the Geopolitical Landscape: An In-Depth Analysis of Australia's Strategic Position
International Journal of Science and Society, 2023 Australia's strategic position in the global geopolitical landscape is a dynamic and multifaceted subject, encompassing factors such as geography, economics, politics, and security. This comprehensive journal article, titled "Navigating the Geopolitical Landscape: An In-Depth Analysis of Australia's Strategic Position," delves deep into these intricate
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Strategic planning tools and techniques in Jordan: awareness and use
, 2008 This paper aims to explore the awareness and use of strategic planning tools and techniques by Jordanian public companies in the financial, service, and industrial sectors.
Jehad S. Aldehayyat +4 more
core +1 more source
Teaching the history of strategic management [PDF]
, 2020 INTRODUCTION When learning about strategic management, it is not only important to study the main concepts and theories but also their historical evolution.
Maijanen, Päivi, Päivi Maijanen
core +1 more source
Strategic control model in the shipbuilding industry [PDF]
مطالعات مدیریت راهبردیShipbuilding companies need deep knowledge of strategic control in their industry to succeed over their foreign and domestic competitors. Unfortunately, most of them do not have sufficient knowledge of the topics related to strategy and strategic control
Vahid Khashei Varnamkhasti +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
How Strategic Issues Emerge in Organizution’s Key Decision Makers’ Agenda [PDF]
بهبود مدیریت, 2015 This research is conducted in response to this question that why only some particular issues are taken into consideration in organizations, or what process makes senior managers to look at cases around them as strategic ones.
Bahareh Abedin +3 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Cleaner Environmental SystemsThis study investigates why digital transformation often leads to inconsistent results in traditional industries. While many assume that technology always improves performance, most research relies on simple ''checklists'' of technology adoption (breadth)
Wenbo Hu +2 more
doaj +1 more source