Results 131 to 140 of about 818,638 (305)
Melbourne urban development: policy statement for EPBC Act referrals [PDF]
Actions considered under this policy include urban, commercial and light industrial developments and infrastructure directly servicing such development (roads, pipelines and other utilities).
core
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Strategic Environmental Indicators for Transport and their Evaluation - Qualitative Decision Aiding for SEA [PDF]
This paper explores to what extent the ordinal multi-criteria decision aid method ELECTRE III can help in strategic assessments of transport’s environmental performance.
Borken, Jens
core
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The protocol on strategic environmental assessment: a matter of good governance [PDF]
De Mulder, Jan
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Transport infrastructure SEA in The Netherlands between procedure, process and content [PDF]
Experience with the EU Strategic Environmental Assessment directive is emerging. In the Netherlands it has been applied to large transport since 2005. In 2006, an evaluation of the organization of this process was done.
Nooteboom, S.G. (Sibout)
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

