Results 121 to 130 of about 9,722,264 (303)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Environmental Sensitivity Mapping: Supporting evidence-based Strategic Environmental Assessment and spatial planning

open access: yes
In the context of the global climate and biodiversity emergencies, there is a significant impetus on planning departments and governmental agencies to ensure that environmental awareness is at the heart of decision-making.
González Del Campo, Ainhoa
core   +1 more source

Strategic environmental assessment in urban development Case study: (Zahedan city) [PDF]

open access: yesعلوم محیطی, 2018
Introduction: Environmental problems are one of the most important issues in major cities, metropolises and it is the result of confliction with the natural environment because urban development is necessarily associated with the domination of buildings,
Zohreh Fanni   +2 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Designing a management framework for Strategic Environmental Assessment of urban plans in China

open access: yes, 2009
Based on the revision of theMethods for Urban Plan Formulation and the Technical Guidelines of Environmental Impact Assessment for UrbanMaster Plan (in draft), this paper proposes a management framework for Strategic Environmental Assessment (SEA) of ...
Ou-Yang, L   +13 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Overview of Strategic Environmental Assessment (SEA) systems in SEE countries [PDF]

open access: yesArhitektura i Urbanizam, 2005
Strategic Environmental Assessment (SEA) represents a significant tool for environmental evaluation of plans and programs. Inclusion of mandatory SEA in national legislative represents at the same time important prerequisite for synchronization with ...
Maričić Tamara, Josimović Boško
doaj  

Strategic environmental assessment: Effective planning instrument or lost concept

open access: yes, 2002
After its 'invention' as a fairly clearly defined instrument for assessing the environmental impacts of policies, plans and programmes in the 1980s, at the end of the 1990s SEA appeared more an undefined concept than a clear and effective planning ...
Fischer, Thomas B., Seaton, Kim
core   +1 more source

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