Results 111 to 120 of about 9,722,264 (303)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

METHODOLOGY OF THE ENTERPRISE ADAPTATION STRATEGY DETERMINING

open access: yesEconomics & Education, 2019
This research paper reveals the step-by-step method of retail enterprises strategy adaptation determining. Alternatives of retail enterprise strategic goals achieving are substantiated in terms of adaptation to environmental factors effect for of retail
Victoria Grosul, Timur Askerov
doaj  

Keynote: Strategic Environmental Assessment

open access: yes, 2018
ATLAS work package 7 presentation at ATLAS 3rd General Assembly Strategic Environmental Assessment (SEA), as set forth, e.g., by EU Directive 2001/42/EC on the assessment of the effects of certain plans and programmes on the environment, stems from the evaluation of transboundary environmental impacts.
Andrade, Francisco   +1 more
openaire   +1 more source

Impacts of region-wide urban development on biodiversity in strategic environmental assessment

open access: yes, 2005
In urbanising regions, urban sprawl and infrastructure cause profound alterations of natural habitats. Initial decisions on urban expansion and major infrastructure investments are often made on a strategic level where the long-term development of a ...
Brokking, Peter,   +3 more
core   +1 more source

Great Barrier Reef Region Strategic Assessment: Program report [PDF]

open access: yes, 2014
The purpose of this report is to outline the Great Barrier Reef Marine Park Authority’s 25-year management program to protect and manage the Great Barrier Reef, including relevant matters of national environmental significance.

core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Environmental assessment of the Alaskan continental shelf.

open access: yes, 1978
Mode of access ...
Outer Continental Shelf Environmental Assessment Program   +2 more
core  

What is wrong with EIA and SEA anyway? A sceptic's perspective on sustainability assessment [PDF]

open access: yes, 2009
Environmental impact assessment (EIA) was initially introduced as an advocacy instrument for the biophysical environment in project decision-making. Strategic environmental assessment (SEA) evolved with a similar mission for strategic level proposals ...
Fischer, T.B., Morrison-Saunders, A.
core  

Strategic environmental assessment in Swedish municipal planning. Trends and challenges

open access: yes, 2018
More than a decade after the implementation of the EU Directive on Strategic Environmental Assessment (SEA) into Swedish legislation, a comprehensive study has been conducted to analyze the development of SEA practice in municipal planning.
Wallström, J.,   +5 more
core   +1 more source

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