Results 31 to 40 of about 7,964 (256)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
AestimumStrategic Environmental Assessment (SEA) is a well-established procedure to support Decision Makers (DMs) in considering and evaluating the effects of Policies, Plans, and Programs (PPPs) on the environment, along with social and economic considerations,
Antonio Boggia +3 more
doaj +1 more source
Commonwealth Journal of Local Governance, 2012 If Strategic Environmental Assessment (SEA) to be effective and fulfil in the spirit of its governing EU Directive 2001/42/EC, cooperative and inclusive attitudes are essential.
Corrado Zoppi
doaj +1 more source
Advances in Implementing Strategic Environmental Assessment (SEA) Techniques in Central America and the Caribbean [PDF]
Sustainability, 2020 The use of Strategic Environmental Assessment (SEA) systems is essential to ensure the sustainability of plans, programs and policies. This works shows, for the first time in the scientific literature, a joint vision of the current situation of SEA systems in Costa Rica, El Salvador, Guatemala, Panama and the Dominican Republic.
Javier Rodrigo-Ilarri +3 more
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Jurnal Pembangunan Wilayah dan Kota, 2021 Strategic Environmental Assessment (SEA) is a process by evaluating environmental impacts and ensuring that the principles of sustainability are integrated in decision making.
Paulus Bimo Wijayanto, Maryono Maryono
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source