Results 41 to 50 of about 11,053,990 (295)
If Strategic Environmental Assessment (SEA) to be effective and fulfil in the spirit of its governing EU Directive 2001/42/EC, cooperative and inclusive attitudes are essential.
Corrado Zoppi
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Developing and testing a policy environmental assessment checklist for biodiversity conservation [PDF]
Strategic environmental assessment (SEA) and policy environmental assessment (PEA), the term used to describe the application of SEA at the policy level, are widely accepted as means of including environmental concerns in decision-making.
Genter, S., Moore, S.A., Bailey, J.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Strategic Environmental Assessment (SEA) is a process by evaluating environmental impacts and ensuring that the principles of sustainability are integrated in decision making.
Paulus Bimo Wijayanto, Maryono Maryono
doaj +1 more source
Conceptualising sustainability assessment [PDF]
Sustainability assessment is being increasingly viewed as an important tool to aid in the shift towards sustainability. However, this is a new and evolving concept and there remain very few examples of effective sustainability assessment processes ...
Pope, J. +2 more
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Civic environmental pragmatism: a dialogical framework for strategic environmental assessment [PDF]
Questions of uncertainty and value conflict are increasingly pervasive challenges confronting policy makers seeking to address the range of environmental problems generated by contemporary technological systems.
Wallington, Tabatha Jean
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

