Results 41 to 50 of about 7,964 (256)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Disaster Prevention in Urban Environments
European Journal of Spatial Development, 2004 Disasters always have very undesirable consequences, especially when they occur in urban environments. This paper discusses some problems with regard to disaster prevention policy in the Netherlands.
Henk Voogd
doaj +3 more sources
Strategic Environmental Assessment (SEA): Seeking Sustainability
New Directions for EvaluationABSTRACTThe world is currently facing wicked problems caused by humanities’ environmental footprint. Strategic Environmental Assessment (SEA) is a holistic, systematic high‐level planning and decision‐making instrument designed to assess impacts of wicked problems, and the strategic actions developed to address them.
Julianne Kealey, Lyn Alderman
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Strategic environmental assessment and monitoring: Arctic key gaps and bridging pathways
Environmental Research Letters, 2013 The Arctic region undergoes rapid and unprecedented environmental change. Environmental assessment and monitoring is needed to understand and decide how to mitigate and/or adapt to the changes and their impacts on society and ecosystems.
Juan Azcárate +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Aspectos ambientais no Plano Nacional de Logística e Transporte do Brasil
Desenvolvimento e Meio Ambiente, 2015 The Brazilian government has been heavily investing in transportation infrastructure. According to environmental laws, this kind of enterprise must do an environmental impact assessment (EIA). However, the EIA is a regulatory measure applied post-project,
Silvana Zioni +1 more
doaj +1 more source
Strategic environmental assessment as an instrument for enhacement of public participation in planning [PDF]
Spatium, 2007 The paper presents an overview of experiences of public participation within planning, summarized in the "ladder of citizen participation". Further, considering that Strategic Environmental Assessment (SEA) is seen as an instrument for operationalizing ...
Crnčević Tijana
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source