Results 41 to 50 of about 12,532 (228)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A critical analysis of purchasing arrangements in Kenya: the case of micro health insurance

open access: yesBMC Health Services Research, 2019
Background Strategic purchasing can ensure that financial resources are used in a way that optimally enhances the attainment of health system goals.
Kenneth Munge   +3 more
doaj   +1 more source

Strategic Purchasing and Health System Efficiency: Prospects for Health Sector Reform in Latvia

open access: yesWSEAS TRANSACTIONS ON BUSINESS AND ECONOMICS, 2020
Strategic purchasing is a significant part of any health policy and health financing reform, which theoretically may have an impact on optimization of cost-effective provision of health care services while simultaneously maximizing population health. The payment model has a direct impact on the delivery of health services.
Māra Pētersone   +3 more
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Pharmaceutical companies’ views on a health technology assessment (HTA) entity in Saudi Arabia

open access: yesSaudi Pharmaceutical Journal, 2020
Saudi Arabia is undergoing a massive healthcare transformation to fulfill its new, national “Vision 2030.” To align with this objective, Saudi Arabia is establishing a new, independent and evidence-based health technology assessment (HTA) entity to help ...
Hussain Abdulrahman Al-Omar   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Factors affecting health services strategic purchasing for breast cancer patients: a mixed study in Iran

open access: yesCost Effectiveness and Resource Allocation, 2021
Background Inappropriate ways of health services purchasing for cancer patients can be challengeable and costly and seriously affect the access to health services and outcomes.
Samereh Yaghoubian   +3 more
doaj   +1 more source

What is strategic purchasing for health?

open access: yes, 2014
Ever since the publication of the 2000 World Health Report, there has been a growing awareness that health financing is not simply about raising money. Instead, there are three key functions of health financing: revenue generation, pooling and purchasing.
openaire   +1 more source

Status of Quality in Strategic Purchasing in the Health System: A Systematic Review

open access: yesRevista del Cuerpo Médico del HNAAA, 2020
Introducction. Strategic purchasing is an important component of financing in the health system. It can enhance productivity, justice, and accountability in the health care delivery in case of considering the quality. This study, which was conducted as a systematic review, was aimed at investigating the status of quality in five domains of strategic ...
Zarei, Zahra   +3 more
openaire   +2 more sources

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