Results 191 to 200 of about 937,785 (295)

Redefining water scarcity through the integrated water strategic resilience index amid climate and conflict pressures. [PDF]

Sci Rep
Verre F, Kumar K, Berndtsson R, Hashemi H.   +3 more
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Patient Perception and Ethical Trade-Offs in Resource Allocation: A Qualitative Study with Conceptual Simulation in a Romanian Municipal Hospital. [PDF]

Healthcare (Basel)
Palamaru AL, Cumpăt CM, Vicol MC, Oprea L, Zouri M, Zouri N, Toader E.   +6 more
europepmc   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

Advanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee, Donghoon Moon, Ziyan Qian, Jinwoo Kim, Changheon Kim, Yeojin Lee, Hyobin Yoo, Richard B. Wilson, Qiye Zheng, Gwan‐Hyoung Lee, Hyejin Jang   +10 more
wiley   +1 more source

Sustaining non-profit organizations: Strategic, managerial and financial perspectives. [PDF]

PLoS One
Harb Y, Khabbaz L, Azouri M, Estephan S.
europepmc   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Generative AI as a conditional job resource under job demands in academic knowledge work: directed content analysis using the job demands-resources framework. [PDF]

Front Artif Intell
Çögenli MZ.
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Strategic resilience in an adaptive SERE & H.E.A.T. course - an explorative study of human performance and resilience. [PDF]

Front Psychiatry
Ziehr S, Merkt PH.
europepmc   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source