Results 21 to 30 of about 480,923 (314)

Safety and efficacy of RNA vaccines: State of the art

Медицинская иммунология, 2021
This review describes principles of action and the method of delivery of mRNA molecules into cells, as well as some of developed RNA vaccines and the results obtained in their study, though they have not been authorized for use yet.
A. V. Blagov, A. A. Bukaeva, V. V. Makarov, Z. V. Bochkaeva   +3 more
doaj   +1 more source

Research of posibilities for implementation of innovations in advanced systems for biomass and other solidwaste treatment [PDF]

Tehnika, 2015
In the start, an aproach of the situation regarding the objectification of innovation is given (from the level of invention and patents), through design to commercialization of new products (development and manufacturing) in accordance with advanced ...
Tomić Radoljub P., Radosavljević Milan Ž., Jovanović Larisa N.   +2 more
doaj   +1 more source

Empirical Analysis of Strategic Management in Inter-Governmental Organization

, 2022
In this study, we present a strategic change theoretical model and empirically validate it in the context of inter-governmental organizations. We followed a survey methodology approach and tested our model hypotheses using exploratory and confirmatory ...
Saade, Raafat, Guan, Hong, Liu, Hao, Ling Wang, James Wan, Hong Guan, Hao Liu, Raafat Saade, Wan, James, Wang, Ling   +9 more
core   +1 more source

Akkermansia muciniphila is a new universal probiotic on the basis of live human commensal gut bacteria: the reality or legend?

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Contemporary information on biology of Akkermansia muciniphila and the role of these gut mucolytic anaerobic bacteria in physiological functions, metabolic and signaling reactions in human health and diseases are presented in the review.
B. A. Shenderov, S. M. Yudin, A. V. Zagaynova, M. P. Shevyreva   +3 more
doaj   +1 more source

Double and Triple Combinations of Broadly Neutralizing Antibodies Provide Efficient Neutralization of All HIV-1 Strains from the Global Panel

Viruses, 2022
The use of broadly neutralizing antibodies (bNAbs) is a promising approach to HIV-1 treatment. In this work, we evaluate the neutralizing activity of the following HIV-1 bNAbs: VCR07-523, N6, PGDM1400, CAP256-VRC26.25, 10-1074, PGT128, 10E8, and DH511 ...
Evgeniya A. Kochina, Felix A. Urusov, Artem A. Kruglov, Dina V. Glazkova, German A. Shipulin, Elena V. Bogoslovskaya   +5 more
doaj   +1 more source

Study of the protective efficacy of CombiMab-2 against human immunodeficiency virus type 1 in mice humanised with CD4⁺ T-lymphocytes

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Despite existing treatment methods, complete eradication of human immunodeficiency virus (HIV) infection remains an unattainable goal due to the high variability of HIV type 1 (HIV-1).
D. S. Leontyev, F. A. Urusov, D. V. Glazkova, B. V. Belugin, O. V. Orlova, R. R. Mintaev, G. M. Tsyganova, E. V. Bogoslovskaya, G. A. Shipulin   +8 more
doaj   +1 more source

A clinical case of reverse left ventricular remodeling in patient with pathogenic TTN mutation. Case report [PDF]

Терапевтический архив
Dilated cardiomyopathy (DCM) is a leading cause of heart failure, sudden cardiac death, and heart transplantation in young patients. The causes of DCM are varied and include genetic factors and metabolic, infectious, toxic and others factors. Today it is
Svetlana N. Nasonova, Aleksei N. Meshkov, Igor V. Zhirov, Yulia F. Osmolovskaya, Anastasiia A. Shoshina, Alan V. Gagloev, Irina H. Dzhumaniiazova, Elena A. Zelenova, Veronika V. Erema, Mariia S. Gusakova, Mikhail V. Ivanov, Mikhail V. Terekhov, Daria A. Kashtanova, Alexsandra I. Nekrasova, Sergey I. Mitrofanov, Andrey S. Shingaliev, Vladimir S. Yudin, Anton A. Keskinov, Nataliya V. Gomyranova, Uliana V. Chubykina, Marat V. Ezhov, Sergey N. Tereshchenko, Sergey M. Yudin, Sergey A. Boytsov   +23 more
doaj   +1 more source

Identification and functional characteristic of SARS-CoV-2-specific T lymphocytes in COVID-19 patients up to 16 months after disease onset

Медицинская иммунология
In cases of respiratory viral infection, along with innate immunity mechanisms, the adaptive immune system plays a crucial role in the body’s defence. The efficiency of its cellular component is crucial for pathogen elimination.
I. S. Vladimirov, A. S. Zhdanova, V. E. Mukhin, V. V. Makarov, V. S. Yudin, S. A. Kraevoy   +5 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

University Environment and Student Entrepreneurship: The Role of Business Experience and Entrepreneurial Self-Efficacy

Вопросы образования, 2015
The study aims to assess how different types of entrepreneurial capital provided by universities affect student involvement in entrepreneurship. The role of university is analyzed from the embeddedness perspective, where purposeful behavior is largely ...
Galina Shirokova, Tatyana Tsukanova, Karina Bogatyreva   +2 more
doaj   +1 more source