Results 41 to 50 of about 480,923 (314)

New pathogenic mutation in LMNA gene: Clinical case of familial cardiomyopathy

Терапевтический архив
We present a clinical case of familial LMNA-associated cardiomyopathy, confirmed by whole genome sequencing. The typical for lamin-associated cardiomyopathy indicates pathogenic nature of the mutation in the first exon of LMNA gene, previously considered
Svetlana Y. Kashtanova, Elena М. Rimskaya, Aleksei N. Meshkov, Nataliia А. Mironova, Irina K. Dzhumaniiazova, Elena A. Zelenova, Veronika V. Daniel', Mikhail V. Ivanov, Daria A. Kashtanova, Vladimir S. Yudin, Anton A. Keskinov, Sergey I. Mitrofanov, Alexsandra I. Akinshina, Yulia N. Vanyushina, Sergey А. Kraevoy, Sergey M. Yudin, Sergey P. Golitsyn   +16 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Dynamic Capabilities and Strategic Management [PDF]

Strategic Management Journal, 1997
Abstract Different approaches to strategy view sources of wealth creation and the essence of the strategic problem faced by firms differently. The competitive forces framework sees the strategic problem in terms of market entry, entry deterrence, and positioning; game-theoretic models view the strategic problem as one of interaction ...
David J. Teece, Gary Pisano, Amy Shuen
openaire   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

AGE-ASSOCIATED VARIABILITY OF CIRCULATING FREE DNA CHARACTERISTICS: GENOME-WIDE ANALYSIS

Journal of Bioinformatics and Genomics
The fragments of circulating free DNA (cfDNA) found in plasma are formed due to the genomic DNA degradation during cellular death. The present study is the first research of age-associated variability of cfDNA characteristics performed on the group of ...
Meshkov I.O., Remizova J.A., Makarova A.S., Primova A.A., Petrova V.A., Bukhanova A.A., Kumar N.A., Ivashechkin A.A., Makhotenko A.V., Snigir E.A., Makarov V.V., Yudin V.S., Keskinov A.A., Yudin S.M.   +13 more
doaj   +1 more source

Contextual Intelligence in Programme and Project Management: A preliminary framework for configuring resources to meet strategic objectives [PDF]

, 2009
Additional research, design and data collection was carried out by David Partington and Arnoud Franken, Cranfield School of ManagementThe purpose of this paper is twofold.
Murray-Webster, Ruth, Lupson, Jonathan, Geraldi, Joana, Maylor, Harvey, Giudici, Alessandro   +4 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Current state of medication treatment practice for heart failure with reduced ejection fraction among cardiologists in Japan: a survey on the relationship between satisfaction levels and adherence to guideline-directed medical therapy

BMC Cardiovascular Disorders
Background The number of patients with heart failure is steadily increasing in parallel with the aging of the population in Japan. This study aimed to assess the level of satisfaction with the latest treatments, identify the factors influencing ...
Satoru Hashimoto, Yoshihiro Motozawa, Toshiki Mano   +2 more
doaj   +1 more source

Corporate distress and turnaround: integrating the literature and directing future research

Business Research, 2017
The topic of corporate distress and turnaround has been of interest to organizational change theory for many decades. This article considers existing reviews in discussing the current body of turnaround literature across multiple research fields and ...
Lars Schweizer, Andreas Nienhaus
doaj   +1 more source

Strategizing for Distributed Knowledge Management [PDF]

, 2003
Knowledge management is rarely found in a strategy context. Although some companies already have introduced the role of a chief knowledge officer, knowledge management is not treated as a strategic endeavour. Furthermore, contributions from an academic point of view are scarce in the field of the strategic issues of knowledge management.
Holm Larsen, Michael, Kühn Pedersen, Mogens   +1 more
openaire   +4 more sources