Results 151 to 160 of about 106,786 (314)
The massive development of indices of multiple deprivation in the UK has provided new data sets which have helped decision makers in shaping innovative and effective strategies and programmes to tackle local deprivation.
Andrea Raffaele Neri
doaj
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Strategic Orientation Model for the Turkish Local e-Governments [PDF]
Increased environmental uncertainty and complexity along with budget constraints requires public organizations to manage strategically as never before.
Aykut, Arslan
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
LEPs Strategic Economic Plans: An initial assessment [PDF]
An initial assessment, by researchers on behalf of the RTPI, of a sample of LEP strategic plans which were submitted this week to the government, has concluded that those LEPs benefiting from a history of larger-than-local partnership working, local ...
Sattar, Zeb +3 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Pompeii municipal council has a highly complex organizational framework; the development of a new municipal urban plan for the city therefore requires the use of innovative instruments capable offacilitating the convergence of different institutions ...
Pasquale Miano
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

