Results 151 to 160 of about 1,020,195 (308)

The importance of Indices of Multiple Deprivation for spatial planning and community regeneration. The example of the Welsh Index of Multiple Deprivation and the related Communities First programme for the Italian system.

Italian Journal of Planning Practice, 2014
The massive development of indices of multiple deprivation in the UK has provided new data sets which have helped decision makers in shaping innovative and effective strategies and programmes to tackle local deprivation.
Andrea Raffaele Neri
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Introduction

Italian Journal of Planning Practice, 2014
Introduction
Massimo Santoro
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Table of contents

Italian Journal of Planning Practice, 2011
Table of ...
Table of Contents
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Urban planning as an instrument for institutional cooperation: the case of Pompeii municipal urban plan

Italian Journal of Planning Practice, 2014
Pompeii municipal council has a highly complex organizational framework; the development of a new municipal urban plan for the city therefore requires the use of innovative instruments capable offacilitating the convergence of different institutions ...
Pasquale Miano
doaj  

The state of strategic plans for the health workforce in Africa. [PDF]

BMJ Glob Health, 2019
Afriyie DO, Nyoni J, Ahmat A.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Toward a new sustainable urban planning

Italian Journal of Planning Practice, 2014
It is clear, as recently established scientifically, that global change is produced byman­made activities carried out on the planet. For a long time, experts have found anomalies and irrationally risky human actions as regards processes which are ...
Romano Fistola
doaj