Combating antimicrobial resistance in Asia: A comprehensive review of strategic action plans, policies, and the role of the WHO. [PDF]
Almawash S.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Guiding Elements for Strengthening Cumulative Impact Assessment Regulations for Offshore Wind Energy. [PDF]
Dibo APA +4 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Reaching the 100 by 2027 target for universal access to rapid molecular diagnostic tests for tuberculosis in Africa: In-sight but out of reach. [PDF]
Mupfumi L +16 more
europepmc +1 more source
Comment for conflict and health don't let sexual and reproductive health in humanitarian and fragile settings become a casualty of aid cuts and crisis fatigue. [PDF]
Tran NT +5 more
europepmc +1 more source
Evaluating institutional planning around collegiate recovery programs: considerations of student awareness and a socio-ecological framework. [PDF]
Prior A +5 more
europepmc +1 more source

