Results 71 to 80 of about 2,195,724 (296)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Best Selection of Strategic Plans in Balanced Scorecard Using Goal Programming Model

open access: yes, 2009
In increasingly competitive business environments, many organizations adopt the strategic planning approach to strive for business excellence. On the other hand achievement and implementation of strategies can perform an important role for the purpose of
Jassbi, J., Daniel, J., Yusuff, R. M.
core  

Examining Collection-Related Language within Academic Library Strategic Plans

open access: yesPennsylvania Libraries: Research & Practice
Though collections are often identified as a core component for academic libraries, studies show that shifting priorities have taken some attention away from the traditional aspects of collections (ACRL Research Planning and Review Committee, 2024 ...
Anne Larrivee
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

WSU colleges: Strategic plans

open access: yes, 2016
Includes strategic plans developed by WSU's colleges and departments during a Phase II strategic planning initiative (2013-2014.)W. Frank Barton School of Business -- College of Education -- College of Engineering -- College of Fine Arts -- College of ...
Office of the President   +2 more
core  

Güneydoğu Anadolu Bölgesi’ndeki büyükşehir belediyelerinin stratejik planlarının su yönetimi bağlamında analizi

open access: yesAfyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi
İklim değişikliği, kuraklık, seller, yangınlar gibi olağanüstü olaylar sonucunda insan için vazgeçilmez olan suya duyulan ihtiyaç daha da artmakta ve suyun yönetimi önem kazanmaktadır.
Hülya Küçük Bayraktar
doaj  

Prioritizing Strategic Objectives and Projects in Higher Education Institutions: A New Hybrid Fuzzy MEREC-G-TOPSIS Approach

open access: yesIEEE Access
Higher education institutions (HEIs) aim to achieve a significant impact on research, learning, teaching, and community services, which are core elements of their strategic plans. Determining the priorities of strategic objectives and related projects is
Reda M. S. Abdelaal   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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