Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Strategic purchasing model for industrial SMEs
Hankinta on yrityksen ulkoisten resurssien hallintaa. Organisaation ulkopuolelta hankitut resurssit muodostavat tavallisesti valtaosan kokonaiskustannuksista, joten hankintojen johtamisella on suuri merkitys yrityksen kannattavuudelle.
Kivikannisto, Sanna
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
The Management Of Successful Strategic Alliances In Supply Chain Management Networks (...) [PDF]
(WP09/02 Clave pdf) This study addresses the issue of what are the key success factors in developing strategic supplier alliances following Monczka et al(1998) perspective of the buying company.
LUIS EDUARDO SOLIS GALVAN
core
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Factors affecting health services strategic purchasing for breast cancer patients: a mixed study in Iran. [PDF]
Yaghoubian S +3 more
europepmc +1 more source
A strategic household purchase: consumer house buying behavior [PDF]
The aim of this study is to examine consumer house-buying behavior from the consumers’ perspective. In view of the existing literature exploring consumer decision making, the purpose of this research was threefold: (a) to propose a conceptual model of consumer decision making within the frame of consumer behavior; (b) to gain knowledge of factors ...
Mateja Kos Koklic, Irena Vida
openaire +2 more sources
Purchasing Power Parity in East Asia: Why all the Fuss? [PDF]
Purchasing Power Parity (PPP) literature is now vast with literally hundreds of papers offering tests for PPP across a broad number of countries. However, despite all the elaborate techniques employed, very little explanation is given as to why PPP is so
Ralf Zurbruegg, Louise Allsopp
core
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source
Scaling-Up Performance-Based Financing in Burkina Faso: From PBF to User Fees Exemption Strategic Purchasing. [PDF]
Seppey M, Ridde V, Somé PA.
europepmc +1 more source

