Results 91 to 100 of about 1,538,190 (269)
Pharmaceutical strategic purchasing: a key to improve access to medicines. [PDF]
Iran J Pharm Res, 2015 Pharmaceuticals are often considered as the most significant cost driver of health care expenditures and at the same time have a major impact on patients’ curative processes and outcomes. Other pieces of evidence emphasize that drugs are the input for the production of good health.
Mehralian G, Bastani P.
europepmc +5 more sources
Jurnal Manajemen Teori dan Terapan, 2016 This study aims to evaluate and prioritize the various forms of strategic programs at the Bandung City Government in strengthening the economy and increasing purchasing power of the people in the city of Bandung based on public policy analysis.
Bayu Kharisma
doaj +1 more source
Repository Strategic Management Business Journal
Strategic Management Business Journal is a forum for researchers in management science, especially in creating the effect of improving organizational performance in human resource management, financial management, and marketing management.
journal, strategic management business
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Procurement and strategy in manufacturing firms [PDF]
, 2012 The strategic role of the Procurement function in manufacturing firms has received increased attention in the literature over the past two decades.
Iyengar, Gopal S.
core +2 more sources
Jurnal Manajemen dan Wirausaha, 2009 The relationship between buyers and suppliers has received considerable attention in recent years. There are fourth major questions being discussed in this research, i.e.
Zeplin Jiwa Husada Tarigan
doaj
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Strategic purchasing in times of public health emergency: lessons from COVID-19. [PDF]
BMJ Glob Health, 2023 Kumah E, Boateng R, Agyei E.
europepmc +1 more source