Results 121 to 130 of about 8,270,702 (310)

Business Process Management

Business & Information Systems Engineering, 2016
W. M. Aalst, Marcello La Rosa, Flávia Maria Santoro   +2 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Strategic perspectives on modularity [PDF]

In this paper we argue that the debate on modularity has come to a point where a consensus is slowly emerging. However, we also contend that this consensus is clearly technology driven. In particular, no room is left for firm strategies.
Florent Catel, Jean-Charles Monateri
core  

Business and Information Technology Alignment Measurement -- a recent Literature Review

, 2019
Since technology has been involved in the business context, Business and Information Technology Alignment (BITA) has been one of the main concerns of IT and Business executives and directors due to its importance to overall company performance ...
A Etien, Ahmad Nadali, B Raadt van der, D Minoli, D Sledgianowski, D Őri, E Umoh, J Luftman, J Luftman, J Luftman, J Luftman, JA Zachman, JC Henderson, JN Luftman, K Doumi, L Cuenca, L-H Thevenet, M El-Mekawy, M Khaiata, M Sarandis, O Avila, O Avila, O Avila, P Mongeon, R Wagter, S Spewak   +25 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Anatomical Injury Clusters in Polytrauma Patients. [PDF]

J Surg Res (Houst), 2022
Birri T, Pape HC, Dennler C, Simmen HP, Vomela J, Chaloupka R, Mica L.   +6 more
europepmc   +1 more source

THE RE-ENGINEERING OF MANAGERIAL PROCESS IN PUBLIC ADMINISTRATION [PDF]

The base of this research was a comparative analyse of the international practices in the field, in order to identify the most important tendencies in public services management.
Ionita Florin, Radu Ioan, Sendroiu Cleopatra   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Human Resources Professional Development within the Knowledge-Based Economy Organizations [PDF]

Through the present paper, we identified and argumented one of the most important consequences of the present business environment: appearance and, gradually, growth of differences between two categories of representants: human resources with high ...
Alexandra STERIU, Alina CIOCARLAN-CHITUCEA, Dan POPESCU, Georgel CALIN, Iulia CHIVU   +4 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source