Results 101 to 110 of about 13,409,388 (337)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Enhancing Knowledge Management Strategies [PDF]
, 2009 {Excerpt} Despite worldwide attention to strategic planning, the notion of strategic practice is surprisingly new. To draw a strategy is relatively easy but to execute it is difficult—strategy is both a macro and a micro phenomenon that depends on ...
Serrat, Olivier
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Circulating microRNAs in Fabry Disease
Scientific Reports, 2019 Fabry disease is an X-linked deficiency of the lysosomal hydrolase alpha-galactosidase A (alpha-Gal). This results in an accumulation of globotriaosylceramide (GL-3/Gb3) in a variety of cells with subsequent functional impairment. The continuous progress
Ke Xiao +10 more
doaj +1 more source
Big Strategy/Small Strategy [PDF]
Strategic Organization, 2012 My title plays on Rumelt’s (2011) instant classic Good Strategy/Bad Strategy. That book focuses on what works well or otherwise for organizations. Big Strategy/Small Strategy switches the focus to different issues. ‘Small Strategy’ is about financial performance, typically of firms in competitive industries.
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Scientific ReportsExcessive fibroblast proliferation and metabolic reprogramming are hallmarks of pathological cardiac remodeling, contributing significantly to impaired cardiac function. This study investigates the role of circular RNAs (circRNAs) in fibroblast metabolic
Arne Schmidt +19 more
doaj +1 more source
Correlation Between Coping Strategies and Quality of Life Among Myocardial Infarction Patients in Nepal [PDF]
, 2011 Objective: To examine the correlation between coping strategies and quality of life (QoL) among patients with myocardial infarction (MI) Method: A descriptive correlational design was used to examine the relationship between coping strategies and QoL ...
Chinnawong, T. (Tippamas) +2 more
core +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source